Anu Loukola
Overview
Explore the profile of Anu Loukola including associated specialties, affiliations and a list of published articles.
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70
Citations
5725
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Recent Articles
1.
Youssef O, Loukola A, Zidi-Mouaffak Y, Tamlander M, Ruotsalainen S, Kilpelainen E, et al.
Lab Invest
. 2024 Jan;
104(4):100325.
PMID: 38220043
Formalin-fixed paraffin-embedded (FFPE) tissues stored in biobanks and pathology archives are a vast but underutilized source for molecular studies on different diseases. Beyond being the "gold standard" for preservation of...
2.
Graham S, Clarke S, Wu K, Kanoni S, Zajac G, Ramdas S, et al.
Nature
. 2023 May;
618(7965):E19-E20.
PMID: 37237109
No abstract available.
3.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature
. 2023 Feb;
615(7952):E19.
PMID: 36829046
No abstract available.
4.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature
. 2023 Jan;
613(7944):508-518.
PMID: 36653562
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%)....
5.
Kanoni S, Graham S, Wang Y, Surakka I, Ramdas S, Zhu X, et al.
Genome Biol
. 2022 Dec;
23(1):268.
PMID: 36575460
Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of...
6.
Koskinen M, Salmi J, Loukola A, Makela M, Sinisalo J, Carpen O, et al.
Sci Rep
. 2022 Nov;
12(1):18492.
PMID: 36323789
The populational heterogeneity of a disease, in part due to comorbidity, poses several complexities. Individual comorbidity profiles, on the other hand, contain useful information to refine phenotyping, prognostication, and risk...
7.
Lahti J, Tuominen S, Yang Q, Pergola G, Ahmad S, Amin N, et al.
Mol Psychiatry
. 2022 Aug;
27(11):4419-4431.
PMID: 35974141
Understanding the genomic basis of memory processes may help in combating neurodegenerative disorders. Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in...
8.
Ramdas S, Judd J, Graham S, Kanoni S, Wang Y, Surakka I, et al.
Am J Hum Genet
. 2022 Aug;
109(8):1366-1387.
PMID: 35931049
A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from...
9.
Graham S, Clarke S, Wu K, Kanoni S, Zajac G, Ramdas S, et al.
Nature
. 2021 Dec;
600(7890):675-679.
PMID: 34887591
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use. Despite advances in prevention and treatment, in...
10.
Leskela J, Toppila I, Harma M, Palviainen T, Salminen A, Sandholm N, et al.
J Am Heart Assoc
. 2021 Oct;
10(21):e022482.
PMID: 34668383
Background Translocation of lipopolysaccharide from gram-negative bacteria into the systemic circulation results in endotoxemia. In addition to acute infections, endotoxemia is detected in cardiometabolic disorders, such as cardiovascular diseases and...