Antti P Aalto
Overview
Explore the profile of Antti P Aalto including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
400
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Recent Articles
1.
Schreiner W, Pagliuso D, Garrigues J, Chen J, Aalto A, Pasquinelli A
Nucleic Acids Res
. 2019 Aug;
47(18):9829-9841.
PMID: 31396626
Elevated temperatures activate a heat shock response (HSR) to protect cells from the pathological effects of protein mis-folding, cellular mis-organization, organelle dysfunction and altered membrane fluidity. This response includes activation...
2.
Aalto A, Nicastro I, Broughton J, Chipman L, Schreiner W, Chen J, et al.
PLoS Genet
. 2018 Jun;
14(6):e1007379.
PMID: 29927939
Argonaute (AGO) proteins partner with microRNAs (miRNAs) to target specific genes for post-transcriptional regulation. During larval development in Caenorhabditis elegans, Argonaute-Like Gene 1 (ALG-1) is the primary mediator of the...
3.
Fonslow B, Moresco J, Tu P, Aalto A, Pasquinelli A, Dillin A, et al.
WormBook
. 2014 Jun;
:1-18.
PMID: 24967700
Mass spectrometry (MS)-based shotgun proteomics is an enabling technology for the study of C. elegans proteins. When coupled with co-immunoprecipitation (CoIP), new interactions and functions among proteins can be discovered....
4.
Aalto A, Bitto D, Ravantti J, Bamford D, Huiskonen J, Oksanen H
Proc Natl Acad Sci U S A
. 2012 Apr;
109(18):7079-84.
PMID: 22509017
The multitude of archaea and bacteria inhabiting extreme environments has only become evident during the last decades. As viruses apply a significant evolutionary force to their hosts, there is an...
5.
Aalto A, Pasquinelli A
Curr Opin Cell Biol
. 2012 Apr;
24(3):333-40.
PMID: 22464106
During the past decade, it has become evident that small non-coding RNAs (ncRNAs) participate in widespread and essential regulatory mechanisms in most eukaryotic cells. Novel classes of small RNAs, their...
6.
Lee H, Aalto A, Yang Q, Chang S, Huang G, Fisher D, et al.
PLoS Biol
. 2010 Oct;
8(10).
PMID: 20957187
The production of aberrant RNA (aRNA) is the initial step in several RNAi pathways. How aRNA is produced and specifically recognized by RNA-dependent RNA polymerases (RdRPs) to generate double-stranded RNA...
7.
Aalto A, Poranen M, Grimes J, Stuart D, Bamford D
J Biol Chem
. 2010 Jul;
285(38):29367-74.
PMID: 20647305
QDE-1 is an RNA- and DNA-dependent RNA polymerase that has functions in the RNA silencing and DNA repair pathways of the filamentous fungus Neurospora crassa. The crystal structure of the...
8.
Nygardas M, Vuorinen T, Aalto A, Bamford D, Hukkanen V
J Gen Virol
. 2009 Jun;
90(Pt 10):2468-2473.
PMID: 19553393
Coxsackievirus B3 (CBV3) is a member of the human enterovirus B species and a common human pathogen. Even though much is known about the enteroviral life cycle, no specific drugs...
9.
Lee H, Chang S, Choudhary S, Aalto A, Maiti M, Bamford D, et al.
Nature
. 2009 May;
459(7244):274-7.
PMID: 19444217
RNA interference pathways use small RNAs to mediate gene silencing in eukaryotes. In addition to small interfering RNAs (siRNAs) and microRNAs, several types of endogenously produced small RNAs have important...
10.
Sarin L, Poranen M, Lehti N, Ravantti J, Koivunen M, Aalto A, et al.
Nucleic Acids Res
. 2009 Jan;
37(4):1182-92.
PMID: 19129226
The RNA-dependent RNA polymerase (RdRP) of double-stranded RNA (dsRNA) viruses performs both RNA replication and transcription. In order to initiate RNA polymerization, viral RdRPs must be able to interact with...