David Veesler
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Explore the profile of David Veesler including associated specialties, affiliations and a list of published articles.
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199
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21599
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Recent Articles
1.
Liu C, Park Y, Ma C, Stuart C, Gen R, Sun Y, et al.
bioRxiv
. 2025 Mar;
PMID: 40027745
Dipeptidyl peptidase-4 (DPP4) is a well-established receptor for several MERS-related coronaviruses (MERSr-CoVs) isolated from humans, camels, pangolins, and bats (1-6). However, the receptor usage of many genetically diverse bat MERSr-CoVs...
2.
Khmelinskaia A, Bethel N, Fatehi F, Mallik B, Antanasijevic A, Borst A, et al.
Nat Struct Mol Biol
. 2025 Feb;
PMID: 40011747
Many naturally occurring protein assemblies have dynamic structures that allow them to perform specialized functions. Although computational methods for designing novel self-assembling proteins have advanced substantially over the past decade,...
3.
Park Y, Liu C, Lee J, Brown J, Ma C, Liu P, et al.
Cell
. 2025 Feb;
PMID: 39922192
DPP4 was considered a canonical receptor for merbecoviruses until the recent discovery of African bat-borne MERS-related coronaviruses using ACE2. The extent and diversity of ACE2 utilization among merbecoviruses and their...
4.
Ma C, Liu C, Park Y, Tang J, Chen J, Xiong Q, et al.
Cell
. 2025 Feb;
PMID: 39922191
The angiotensin-converting enzyme 2 (ACE2) receptor is shared by various coronaviruses with distinct receptor-binding domain (RBD) architectures, yet our understanding of these convergent acquisition events remains elusive. Here, we report...
5.
Gen R, Addetia A, Asarnow D, Park Y, Quispe J, Chan M, et al.
bioRxiv
. 2025 Jan;
PMID: 39868184
SARS-CoV-2 nonstructural protein 1 (nsp1) promotes innate immune evasion by inhibiting host translation in human cells. However, the role of nsp1 in other host species remains elusive, especially in bats...
6.
Dowling Q, Park Y, Fries C, Gerstenmaier N, Ols S, Yang E, et al.
Nature
. 2024 Dec;
638(8050):553-561.
PMID: 39695230
Discrete protein assemblies ranging from hundreds of kilodaltons to hundreds of megadaltons in size are a ubiquitous feature of biological systems and perform highly specialized functions. Despite remarkable recent progress...
7.
Chao C, Sprouse K, Miranda M, Catanzaro N, Hubbard M, Addetia A, et al.
Cell Rep
. 2024 Dec;
43(12):115036.
PMID: 39644492
Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus that causes severe respiratory illness in humans. There are no licensed vaccines against MERS-CoV and only a few candidates in phase...
8.
Ragotte R, Tortorici M, Catanzaro N, Addetia A, Coventry B, Froggatt H, et al.
bioRxiv
. 2024 Nov;
PMID: 39574666
Middle-East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic pathogen with 36% case-fatality rate in humans. No vaccines or specific therapeutics are currently approved to use in humans or the camel...
9.
Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses
Rexhepaj M, Asarnow D, Perruzza L, Park Y, Guarino B, Mccallum M, et al.
Immunity
. 2024 Nov;
57(12):2914-2927.e7.
PMID: 39488210
Porcine delta-coronavirus (PDCoV) spillovers were recently detected in febrile children, underscoring the recurrent zoonoses of divergent CoVs. To date, no vaccines or specific therapeutics are approved for use in humans...
10.
McCallum M, Veesler D
bioRxiv
. 2024 Nov;
PMID: 39484573
In the absence of effective vaccines, human-infecting members of the Herpesvirus family cause considerable morbidity and mortality worldwide. Herpesvirus infection relies on receptor engagement by a gH/gL glycoprotein complex which...