Mirjam H Koster
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Explore the profile of Mirjam H Koster including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
93
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0
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Recent Articles
1.
Halmos B, La Rose A, Methorst D, Groenen A, Nakladal D, Bazioti V, et al.
Circ Res
. 2025 Feb;
136(5):491-507.
PMID: 39931819
Background: Smooth muscle cells (SMCs) regulate blood flow distribution via vasoconstriction mediated by α-ARs (α-adrenergic receptors). Plasma membrane cholesterol accumulation affects α-AR signaling and promotes loss of SMC contractile markers...
2.
Yntema T, Eijgenraam T, Kloosterhuis N, Havinga R, Koster M, Hovingh M, et al.
Sci Rep
. 2025 Jan;
15(1):2100.
PMID: 39815082
Bile acids (BAs) play important roles in the context of lipid homeostasis and inflammation. Based on extensive preclinical mouse studies, BA signaling pathways have been implicated as therapeutic targets for...
3.
Ling C, Versloot C, Arvidsson Kvissberg M, Hu G, Swain N, Horcas-Nieto J, et al.
EBioMedicine
. 2023 Sep;
96:104809.
PMID: 37738832
Background: The intestine of children with severe malnutrition (SM) shows structural and functional changes that are linked to increased infection and mortality. SM dysregulates the tryptophan-kynurenine pathway, which may impact...
4.
Postmus A, Kruit J, Eilers R, Havinga R, Koster M, Johmura Y, et al.
Toxicol Appl Pharmacol
. 2023 Apr;
468:116531.
PMID: 37088304
Cancer survivors who received chemotherapy, such as the anthracycline doxorubicin (DOX), have an increased risk of developing complications later in life, including the development of chronic metabolic diseases. Although the...
5.
Rutten M, Lei Y, Hoogerland J, Bloks V, Yang H, Bos T, et al.
Cancer Metab
. 2023 Apr;
11(1):5.
PMID: 37085901
Background: Glycogen storage disease type 1a (GSD Ia) is an inborn error of metabolism caused by a defect in glucose-6-phosphatase (G6PC1) activity, which induces severe hepatomegaly and increases the risk...
6.
Tol A, Hribar K, Kruit J, Bongiovanni L, Vieira-Lara M, Koster M, et al.
J Physiol
. 2023 Apr;
601(10):1761-1780.
PMID: 37010236
Hyperglycaemia in pregnancy (HIP) is a pregnancy complication characterized by mild to moderate hyperglycaemia that negatively impacts short- and long-term health of mother and child. However, relationships between severity and...
7.
Horcas-Nieto J, Versloot C, Langelaar-Makkinje M, Gerding A, Blokzijl T, Koster M, et al.
Biochim Biophys Acta Mol Basis Dis
. 2022 Dec;
1869(3):166635.
PMID: 36581145
No abstract available.
8.
van Zwol W, Rimbert A, Wolters J, Smit M, Bloks V, Kloosterhuis N, et al.
Hepatology
. 2022 Sep;
78(5):1418-1432.
PMID: 36053190
Background And Aims: The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in...
9.
La Rose A, Groenen A, Halmos B, Bazioti V, Rutten M, Krishnamurthy K, et al.
Mol Genet Metab Rep
. 2022 Jul;
31:100872.
PMID: 35782606
Glycogen storage disease type 1a (GSD Ia) is an inborn error of carbohydrate metabolism. Despite severe hyperlipidemia, GSD Ia patients show limited atherogenesis compared to age-and-gender matched controls. Employing a...
10.
Bazioti V, La Rose A, Maassen S, Bianchi F, de Boer R, Halmos B, et al.
Nat Commun
. 2022 Jul;
13(1):3799.
PMID: 35778407
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During aging, T cells accumulate cholesterol, potentially affecting inflammation. However, the effect of cholesterol efflux pathways mediated by ATP-binding cassette A1...