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Annick Itie-Youten

Explore the profile of Annick Itie-Youten including associated specialties, affiliations and a list of published articles. Areas
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Citations 710
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Recent Articles
1.
McIlwain D, Lang P, Maretzky T, Hamada K, Ohishi K, Maney S, et al.
Science . 2012 Jan; 335(6065):229-32. PMID: 22246778
Innate immune responses are vital for pathogen defense but can result in septic shock when excessive. A key mediator of septic shock is tumor necrosis factor-α (TNFα), which is shed...
2.
McIlwain D, Pan Q, Reilly P, Elia A, McCracken S, Wakeham A, et al.
Proc Natl Acad Sci U S A . 2010 Jun; 107(27):12186-91. PMID: 20566848
Smg1 is a PI3K-related kinase (PIKK) associated with multiple cellular functions, including DNA damage responses, telomere maintenance, and nonsense-mediated mRNA decay (NMD). NMD degrades transcripts that harbor premature termination codons...
3.
Wilhelm M, Rufini A, Wetzel M, Tsuchihara K, Inoue S, Tomasini R, et al.
Genes Dev . 2010 Mar; 24(6):549-60. PMID: 20194434
Mice with a complete deficiency of p73 have severe neurological and immunological defects due to the absence of all TAp73 and DeltaNp73 isoforms. As part of our ongoing program to...
4.
Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung C, et al.
Genes Dev . 2008 Sep; 22(19):2677-91. PMID: 18805989
The Trp53 gene family member Trp73 encodes two major groups of protein isoforms, TAp73 and DeltaNp73, with opposing pro- and anti-apoptotic functions; consequently, their relative ratio regulates cell fate. However,...
5.
Tsuchihara K, Lapin V, Bakal C, Okada H, Brown L, Hirota-Tsuchihara M, et al.
Cancer Res . 2005 Aug; 65(15):6685-91. PMID: 16061649
We used DNA microarray screening to identify Ckap2 (cytoskeleton associated protein 2) as a novel p53 target gene in a mouse erythroleukemia cell line. DNA damage induces human and mouse...