Annemieke A Michels
Overview
Explore the profile of Annemieke A Michels including associated specialties, affiliations and a list of published articles.
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13
Citations
586
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Recent Articles
1.
Nguyen D, Buisine N, Fayol O, Michels A, Bensaude O, Price D, et al.
BMC Mol Cell Biol
. 2021 Aug;
22(1):43.
PMID: 34461828
Background: The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA polymerase II elongation. Although its primary sequence varies...
2.
Michels A, Bensaude O
Transcription
. 2018 Jan;
9(4):262-271.
PMID: 29345523
Hexim1 acts as a tumor suppressor and is involved in the regulation of innate immunity. It was initially described as a non-coding RNA-dependent regulator of transcription. Here, we detail how...
3.
Michaud L, Ludwig G, Berney S, Rodrigues S, Niquille A, Santschi V, et al.
Pharm Pract (Granada)
. 2017 Jan;
14(4):822.
PMID: 28042353
Background: Lack of adherence to medication is a trigger of graft rejection in solid-organ transplant (SOT) recipients. Objective: This exploratory study aimed to assess whether a biopsychosocial evaluation using the...
4.
Michels A
Biochem Soc Trans
. 2011 Mar;
39(2):487-91.
PMID: 21428925
Yeast and mammalian MAF1 are both regulated by the TOR (target of rapamycin) pathway. However, the exact mechanisms of regulation diverge at TOR, with yeast Maf1 phosphorylated mainly by the...
5.
Michels A, Robitaille A, Buczynski-Ruchonnet D, Hodroj W, Reina J, Hall M, et al.
Mol Cell Biol
. 2010 Jun;
30(15):3749-57.
PMID: 20516213
mTORC1 is a central regulator of growth in response to nutrient availability, but few direct targets have been identified. RNA polymerase (pol) III produces a number of essential RNA molecules...
6.
Lau J, Lew Q, Diribarne G, Michels A, Dey A, Bensaude O, et al.
Cell Cycle
. 2009 Jul;
8(14):2247-54.
PMID: 19617712
Hexamethylene bis-acetamide inducible protein 1 (HEXIM1) is an inhibitor of the positive transcription elongation factor b (P-TEFb), which controls RNA polymerase II transcription and human immunodeficiency virus Tat transactivation. In...
7.
Michels A, Bensaude O
Biotechnol J
. 2008 Jul;
3(8):1022-32.
PMID: 18655042
The positive transcription elongation factor (P-TEFb) consists of CDK9, a cyclin-dependent kinase and its cyclin T partner. It is required for transcription of most class II genes. Its activity is...
8.
Bierhoff H, Dundr M, Michels A, Grummt I
Mol Cell Biol
. 2008 Jun;
28(16):4988-98.
PMID: 18559419
The protein kinase casein kinase 2 (CK2) phosphorylates different components of the RNA polymerase I (Pol I) transcription machinery and exerts a positive effect on rRNA gene (rDNA) transcription. Here...
9.
10.
Dulac C, Michels A, Fraldi A, Bonnet F, Nguyen V, Napolitano G, et al.
J Biol Chem
. 2005 Jul;
280(34):30619-29.
PMID: 15994294
The positive transcription elongation factor (P-TEFb) comprises a kinase, CDK9, and a Cyclin T1 or T2. Its activity is inhibited by association with the HEXIM1 or HEXIM2 protein bound to...