Anne-Claire Groo
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Explore the profile of Anne-Claire Groo including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
147
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Recent Articles
1.
Boudrioua A, Baetz B, Desmadril S, Goulard C, Groo A, Lombard C, et al.
iScience
. 2025 Mar;
28(3):111922.
PMID: 40034853
Antibiotic resistance is a major threat to human health and new drugs are urgently needed. Ideally, these drugs should have several cellular targets in pathogens, decreasing the risk of resistance...
2.
Groo A, Curel T, Malzert-Freon A, Seguy L, Bento O, Corvaisier S, et al.
Commun Biol
. 2025 Feb;
8(1):155.
PMID: 39893320
Bambuterol is a long-acting anti-asthmatic prodrug which releases terbutaline. Terbutaline is an agonist of the β-adrenergic receptors which is formed by decarbamoylation of bambuterol by butyrylcholinesterase. Inhibition of the latter,...
3.
Hervieu L, Groo A, Bellien J, Guerrot D, Malzert-Freon A
Pharmacol Ther
. 2024 Dec;
266():108773.
PMID: 39647710
The gastrointestinal tract (GIT) plays a pivotal role in the absorption of orally administered drugs, with the small intestine serving as the primary site due to its extensive surface area...
4.
Morel M, Madau M, Le Cerf D, Dulong V, Groo A, Malzert-Freon A, et al.
J Mater Chem B
. 2024 Feb;
12(11):2807-2817.
PMID: 38404247
Injectable thermosensitive hydrogels based on hyaluronic acid (HA) grafted with lower critical solution temperature (LCST) polyoxazoline (copolymers of poly(isopropyl--butyl oxazoline)) or P(iPrOx--BuOx) have been elaborated with tunable solution/gel temperature transitions...
5.
Seguy L, Daressy F, Lahlil S, Corvaisier S, Dumontet V, Litaudon M, et al.
Int J Pharm
. 2022 Nov;
630:122433.
PMID: 36436745
MCL-1, an anti-apoptotic member of the BCL-2 protein family, is overexpressed in many types of cancer and contributes to chemotherapy resistance. The drimane derivative NA1-115-7 is a natural compound isolated...
6.
Daressy F, Seguy L, Favre L, Corvaisier S, Apel C, Groo A, et al.
Biomed Pharmacother
. 2022 Aug;
154:113546.
PMID: 35988426
The overexpression of antiapoptotic members (BCL-2, BCL-xL, MCL-1, etc.) of the BCL-2 family contributes to tumor development and resistance to chemotherapy or radiotherapy. Synthetic inhibitors targeting these proteins have been...
7.
Seguy L, Groo A, Malzert-Freon A
Drug Discov Today
. 2022 Mar;
27(6):1575-1589.
PMID: 35227886
Given the continual increase in the number of patients and the lack of curative treatment, the development of new therapies to treat Alzheimer's disease (AD) is becoming ever more urgent....
8.
Seguy L, Guyon L, Maurel M, Verdie P, Davis A, Corvaisier S, et al.
Pharmaceutics
. 2021 Oct;
13(10).
PMID: 34683919
Background And Purpose: The activation of 5-HT receptors with agonists has emerged as a valuable therapeutic strategy to treat Alzheimer's disease (AD) by enhancing the nonamyloidogenic pathway. Here, the potential...
9.
Daressy F, Malard F, Seguy L, Guerineau V, Apel C, Dumontet V, et al.
ChemMedChem
. 2021 Mar;
16(11):1788-1797.
PMID: 33665938
Drimane sesquiterpenoid dialdehydes are natural compounds with antiproliferative properties. Nevertheless, their mode of action has not yet been discovered. Herein, we demonstrate that various drimanes are potent inhibitors of MCL-1...
10.
Seguy L, Groo A, Goux D, Hennequin D, Malzert-Freon A
Pharmaceutics
. 2020 Dec;
12(12).
PMID: 33255606
Among advanced formulation strategies, nanoemulsions are considered useful drug-delivery systems allowing to improve the solubility and the bioavailability of lipophilic drugs. To select safe excipients for nanoemulsion formulation and to...