Anna Zganiacz
Overview
Explore the profile of Anna Zganiacz including associated specialties, affiliations and a list of published articles.
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31
Citations
1137
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Recent Articles
21.
Ngai P, McCormick S, Small C, Zhang X, Zganiacz A, Aoki N, et al.
Infect Immun
. 2007 Feb;
75(5):2244-52.
PMID: 17307945
Gamma interferon (IFN-gamma) is a key cytokine in host defense against intracellular mycobacterial infection. It has been believed that both CD4 and CD8 T cells are the primary sources of...
22.
Santosuosso M, McCormick S, Roediger E, Zhang X, Zganiacz A, Lichty B, et al.
J Immunol
. 2007 Feb;
178(4):2387-95.
PMID: 17277145
Genetic immunization holds great promise for future vaccination against mucosal infectious diseases. However, parenteral genetic immunization is ineffective in control of mucosal intracellular infections, and the underlying mechanisms have remained...
23.
Zhang X, Divangahi M, Ngai P, Santosuosso M, Millar J, Zganiacz A, et al.
Vaccine
. 2006 Oct;
25(7):1342-52.
PMID: 17052817
Plasmid DNA vaccine has been widely explored for tuberculosis immunization but there is a need to develop the ways to improve its immunogenicity. In this study, we have constructed a...
24.
Santosuosso M, McCormick S, Zhang X, Zganiacz A, Xing Z
Infect Immun
. 2006 Jul;
74(8):4634-43.
PMID: 16861651
Parenterally administered Mycobacterium bovis BCG vaccine confers only limited immune protection from pulmonary tuberculosis in humans. There is a need for developing effective boosting vaccination strategies. We examined a heterologous...
25.
Wang J, Thorson L, Stokes R, Santosuosso M, Huygen K, Zganiacz A, et al.
J Immunol
. 2004 Nov;
173(10):6357-65.
PMID: 15528375
Bacillus Calmette-Guerin (BCG) vaccine has failed to control the global tuberculosis (TB) epidemic, and there is a lack of safe and effective mucosal vaccines capable of potent protection against pulmonary...
26.
Wang J, Santosuosso M, Ngai P, Zganiacz A, Xing Z
J Immunol
. 2004 Sep;
173(7):4590-7.
PMID: 15383593
We have investigated whether both primary CD8 T cell activation and CD8 T cell-mediated protection from Mycobacterium tuberculosis challenge could occur in mycobacterial-vaccinated CD4 T cell-deficient (CD4KO) mice. Different from...
27.
Aoki N, Zganiacz A, Margetts P, Xing Z
Infect Immun
. 2004 Apr;
72(5):2477-83.
PMID: 15102754
DAP12 and its associating molecules MDL-1, TREM-1, and TREM-2 are the recently identified immune regulatory molecules, expressed primarily on myeloid cells including monocytes/macrophages, dendritic cells, NK cells, and neutrophils. However,...
28.
Zganiacz A, Santosuosso M, Wang J, Yang T, Chen L, Anzulovic M, et al.
J Clin Invest
. 2004 Feb;
113(3):401-13.
PMID: 14755337
TNF-alpha has long been regarded as a proimmune cytokine involved in antimicrobial type 1 immunity. However, the precise role of TNF-alpha in antimicrobial type 1 immunity remains poorly understood. We...
29.
Chen L, Wang J, Zganiacz A, Xing Z
Infect Immun
. 2003 Dec;
72(1):238-46.
PMID: 14688101
Whether the intranasal (i.n.) route of Mycobacterium bovis BCG vaccination provides better protection against pulmonary tuberculosis than subcutaneous (s.c.) vaccination remains an incompletely solved issue. In the present study, we...
30.
Wang J, Zganiacz A, Xing Z
Vaccine
. 2002 Jul;
20(23-24):2887-98.
PMID: 12126899
The failure of current BCG vaccine in controlling the global tuberculosis (TB) epidemic highlights an urgent need for improved TB vaccine formulations. In this study, we have investigated the effect...