Anna Zganiacz
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Explore the profile of Anna Zganiacz including associated specialties, affiliations and a list of published articles.
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31
Citations
1137
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Recent Articles
11.
Haddadi S, Vaseghi-Shanjani M, Yao Y, Afkhami S, DAgostino M, Zganiacz A, et al.
Front Immunol
. 2019 Sep;
10:2075.
PMID: 31552032
Tissue-resident memory T cells (T) are critical to host defense at mucosal tissue sites. However, the parenteral route of immunization as the most commonly used immunization route in practice is...
12.
Afkhami S, Lai R, DAgostino M, Vaseghi-Shanjani M, Zganiacz A, Yao Y, et al.
J Infect Dis
. 2019 Jun;
220(8):1355-1366.
PMID: 31198944
Background: The development of strategies to accelerate disease resolution and shorten antibiotic therapy is imperative in curbing the global tuberculosis epidemic. Therapeutic application of novel vaccines adjunct to antibiotics represents...
13.
Lai R, Jeyanathan M, Afkhami S, Zganiacz A, Hammill J, Yao Y, et al.
J Immunol
. 2018 Jan;
200(5):1746-1760.
PMID: 29374077
, the pathogen causing pulmonary tuberculosis (TB) in humans, has evolved to delay Th1 immunity in the lung. Although conventional dendritic cells (cDCs) are known to be critical to the...
14.
Yao Y, Lai R, Afkhami S, Haddadi S, Zganiacz A, Vahedi F, et al.
J Infect Dis
. 2017 May;
216(1):135-145.
PMID: 28531291
Background: The translation of preclinically promising novel tuberculosis vaccines to ultimate human applications has been challenged by the lack of animal models with an immune system equivalent to the human...
15.
Khera A, Afkhami S, Lai R, Jeyanathan M, Zganiacz A, Mandur T, et al.
J Immunol
. 2015 Aug;
195(6):2900-7.
PMID: 26268652
Emerging evidence suggests a role of B cells in host defense against primary pulmonary tuberculosis (TB). However, the role of B cells in TB vaccine-induced protective T cell immunity still...
16.
Damjanovic D, Khera A, Afkhami S, Lai R, Zganiacz A, Jeyanathan M, et al.
PLoS One
. 2015 Jun;
10(6):e0131175.
PMID: 26098423
Tuberculosis (TB) remains a global pandemic despite the use of Bacillus Calmette-Guérin (BCG) vaccine, partly because BCG fails to effectively control adult pulmonary TB. The introduction of novel boost vaccines...
17.
Smaill F, Jeyanathan M, Smieja M, Medina M, Thanthrige-Don N, Zganiacz A, et al.
Sci Transl Med
. 2013 Oct;
5(205):205ra134.
PMID: 24089406
There is an urgent need to develop new tuberculosis (TB) vaccines to safely and effectively boost Bacille Calmette-Guérin (BCG)-triggered T cell immunity in humans. AdHu5Ag85A is a recombinant human type...
18.
Shaler C, Horvath C, McCormick S, Jeyanathan M, Khera A, Zganiacz A, et al.
PLoS One
. 2013 Mar;
8(3):e59185.
PMID: 23527127
Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis, is the leading cause of death due to a bacterial pathogen. Emerging epidemiologic evidence suggests that the leading risk factor associated with TB...
19.
Damjanovic D, Divangahi M, Kugathasan K, Small C, Zganiacz A, Brown E, et al.
Am J Pathol
. 2011 Oct;
179(6):2963-76.
PMID: 22001698
Lung immunopathology is the main cause of influenza-mediated morbidity and death, and much of its molecular mechanisms remain unclear. Whereas tumor necrosis factor-α (TNF-α) is traditionally considered a proinflammatory cytokine,...
20.
Mu J, Jeyanathan M, Shaler C, Horvath C, Damjanovic D, Zganiacz A, et al.
J Gene Med
. 2010 Aug;
12(8):693-704.
PMID: 20694950
Background: Virus-vectored vaccine is a powerful activator of CD8 T cell-mediated immunity and is especially amenable to respiratory mucosal immunization, offering hopes for use in humans with diminished helper CD4...