Anna Waller
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Explore the profile of Anna Waller including associated specialties, affiliations and a list of published articles.
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72
Citations
1804
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Recent Articles
21.
Cannon D, Yang J, Mathias S, Ursu O, Mani S, Waller A, et al.
Bioinformatics
. 2017 Apr;
33(16):2601-2603.
PMID: 28398460
Motivation: The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins. Results: We developed TIN-X, the...
22.
Nguyen D, Mathias S, Bologa C, Brunak S, Fernandez N, Gaulton A, et al.
Nucleic Acids Res
. 2016 Dec;
45(D1):D995-D1002.
PMID: 27903890
The 'druggable genome' encompasses several protein families, but only a subset of targets within them have attracted significant research attention and thus have information about them publicly available. The Illuminating...
23.
Sykes D, Kfoury Y, Mercier F, Wawer M, Law J, Haynes M, et al.
Cell
. 2016 Sep;
167(1):171-186.e15.
PMID: 27641501
While acute myeloid leukemia (AML) comprises many disparate genetic subtypes, one shared hallmark is the arrest of leukemic myeloblasts at an immature and self-renewing stage of development. Therapies that overcome...
24.
Sun X, Waller A, Yeatts K, Thie L
Sci Total Environ
. 2015 Dec;
544:185-91.
PMID: 26657364
Pollen has been generally linked to an increased risk for asthma exacerbation. However, the delayed effect (lag), the length of effect duration, and the association heterogeneity by pollen types have...
25.
Oprea T, Sklar L, Agola J, Guo Y, Silberberg M, Roxby J, et al.
PLoS One
. 2015 Nov;
10(11):e0142182.
PMID: 26558612
Rho family GTPases (including Rac, Rho and Cdc42) collectively control cell proliferation, adhesion and migration and are of interest as functional therapeutic targets in numerous epithelial cancers. Based on high...
26.
Chauhan S, Ahmed Z, Bradfute S, Arko-Mensah J, Mandell M, Choi S, et al.
Nat Commun
. 2015 Oct;
6:8620.
PMID: 26503418
Autophagy is a conserved homeostatic process active in all human cells and affecting a spectrum of diseases. Here we use a pharmaceutical screen to discover new mechanisms for activation of...
27.
Wu Y, Stauffer S, Stanfield R, Tapia P, Ursu O, Fisher G, et al.
J Biomol Screen
. 2015 Oct;
21(1):74-87.
PMID: 26442911
A new class of biosensors, fluorogen activating proteins (FAPs), has been successfully used to track receptor trafficking in live cells. Unlike the traditional fluorescent proteins (FPs), FAPs do not fluoresce...
28.
Fuhrmann C, Sugg M, Konrad 2nd C, Waller A
J Community Health
. 2015 Aug;
41(1):146-56.
PMID: 26289379
Extreme heat is the leading cause of weather-related mortality in the U.S. Extreme heat also affects human health through heat stress and can exacerbate underlying medical conditions that lead to...
29.
Hong L, Guo Y, BasuRay S, Agola J, Romero E, Simpson D, et al.
PLoS One
. 2015 Aug;
10(8):e0134317.
PMID: 26247207
Overactive GTPases have often been linked to human diseases. The available inhibitors are limited and have not progressed far in clinical trials. We report here a first-in-class small molecule pan-GTPase...
30.
Emergency Medical Text Classifier: New system improves processing and classification of triage notes
Haas S, Travers D, Waller A, Mahalingam D, Crouch J, Schwartz T, et al.
Online J Public Health Inform
. 2014 Nov;
6(2):e178.
PMID: 25379126
Objective: Automated syndrome classification aims to aid near real-time syndromic surveillance to serve as an early warning system for disease outbreaks, using Emergency Department (ED) data. We present a system...