Anja Ebert
Overview
Explore the profile of Anja Ebert including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
2698
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0
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Recent Articles
1.
Vilstrup A, Gupta A, Rasmussen A, Ebert A, Riedelbauch S, Lukassen M, et al.
Genes Dev
. 2024 Sep;
38(17-20):866-886.
PMID: 39332828
Animal germline development and fertility rely on paralogs of general transcription factors that recruit RNA polymerase II to ensure cell type-specific gene expression. It remains unclear whether gene expression processes...
2.
Schmoellerl J, Barbosa I, Minnich M, Andersch F, Smeenk L, Havermans M, et al.
Blood
. 2022 Sep;
141(5):453-466.
PMID: 36095844
Chromosomal rearrangements involving the MDS1 and EVI1 complex locus (MECOM) on chromosome 3q26 define an aggressive subtype of acute myeloid leukemia (AML) that is associated with chemotherapy resistance and dismal...
3.
Calderon L, Schindler K, Malin S, Schebesta A, Sun Q, Schwickert T, et al.
Sci Immunol
. 2021 Jul;
6(61).
PMID: 34301800
The transcription factor Pax5 controls B cell development, but its role in mature B cells is largely enigmatic. Here, we demonstrated that the loss of Pax5 by conditional mutagenesis in...
4.
Smeenk L, Ottema S, Mulet-Lazaro R, Ebert A, Havermans M, Arricibita Varea A, et al.
Cancer Discov
. 2021 May;
11(11):2868-2883.
PMID: 33980539
In acute myeloid leukemia (AML) with inv(3)(q21;q26) or t(3;3)(q21;q26), a translocated enhancer drives oncogenic expression of . We generated an EVI1-GFP AML model and applied an unbiased CRISPR/Cas9 enhancer scan...
5.
Hill L, Ebert A, Jaritz M, Wutz G, Nagasaka K, Tagoh H, et al.
Nature
. 2020 Jul;
584(7819):142-147.
PMID: 32612238
Nuclear processes, such as V(D)J recombination, are orchestrated by the three-dimensional organization of chromosomes at multiple levels, including compartments and topologically associated domains (TADs) consisting of chromatin loops. TADs are...
6.
Schlager S, Salomon C, Olt S, Albrecht C, Ebert A, Bergner O, et al.
Oncotarget
. 2020 Mar;
11(9):875-890.
PMID: 32180900
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphomas worldwide and is characterized by a high diversity of genetic and molecular alterations. Chromosomal translocations and mutations...
7.
Ayata P, Badimon A, Strasburger H, Duff M, Montgomery S, Loh Y, et al.
Nat Neurosci
. 2018 Jul;
21(8):1049-1060.
PMID: 30038282
The rapid elimination of dying neurons and nonfunctional synapses in the brain is carried out by microglia, the resident myeloid cells of the brain. Here we show that microglia clearance...
8.
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al.
Science
. 2018 Apr;
360(6390):800-805.
PMID: 29622725
Defining direct targets of transcription factors and regulatory pathways is key to understanding their roles in physiology and disease. We combined SLAM-seq [thiol(SH)-linked alkylation for the metabolic sequencing of RNA],...
9.
Fujimura N, Kuzelova A, Ebert A, Strnad H, Lachova J, Machon O, et al.
Dev Biol
. 2017 Nov;
433(1):47-60.
PMID: 29137925
Polycomb repressive complexes maintain transcriptional repression of genes encoding crucial developmental regulators through chromatin modification. Here we investigated the role of Polycomb repressive complex 2 (PRC2) in retinal development by...
10.
Pasquarella A, Ebert A, de Almeida G, Hinterberger M, Kazerani M, Nuber A, et al.
Development
. 2016 Mar;
143(10):1788-99.
PMID: 27013243
The H3K9me3-specific histone methyltransferase Setdb1 impacts on transcriptional regulation by repressing both developmental genes and retrotransposons. How impaired retrotransposon silencing may lead to developmental phenotypes is currently unclear. Here, we...