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Anita G Seto

Explore the profile of Anita G Seto including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 1828
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Recent Articles
1.
Anastasiadou E, Seto A, Beatty X, Hermreck M, Gilles M, Stroopinsky D, et al.
Clin Cancer Res . 2020 Nov; 27(4):1139-1149. PMID: 33208342
Purpose: miRNA-155 is an oncogenic miRNA highly expressed in B-cell malignancies, particularly in the non-germinal center B-cell or activated B-cell subtype of diffuse large B-cell lymphoma (ABC-DLBCL), where it is...
2.
Gallant-Behm C, Piper J, Lynch J, Seto A, Hong S, Mustoe T, et al.
J Invest Dermatol . 2018 Nov; 139(5):1073-1081. PMID: 30472058
MicroRNA-29 (miR-29) negatively regulates fibrosis and is downregulated in multiple fibrotic organs and tissues, including in the skin. miR-29 mimics prevent pulmonary fibrosis in mouse models but have not previously...
3.
Seto A, Beatty X, Lynch J, Hermreck M, Tetzlaff M, Duvic M, et al.
Br J Haematol . 2018 Aug; 183(3):428-444. PMID: 30125933
miR-155, a microRNA associated with poor prognosis in lymphoma and leukaemia, has been implicated in the progression of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL)....
4.
Eding J, Demkes C, Lynch J, Seto A, Montgomery R, Semus H, et al.
Mol Ther . 2017 Feb; 25(3):694-704. PMID: 28202391
MicroRNAs (miRNAs) are important regulators of biology and disease. Recent animal efficacy studies validate the therapeutic benefit of miRNA modulation and underscore the therapeutic value of miRNA-targeting oligonucleotides. However, whether...
5.
Deng L, Blanco F, Stevens H, Lu R, Caudrillier A, McBride M, et al.
Circ Res . 2015 Aug; 117(10):870-883. PMID: 26311719
Rationale: The pathogenesis of pulmonary arterial hypertension (PAH) remains unclear. The 4 microRNAs representing the miR-143 and miR-145 stem loops are genomically clustered. Objective: To elucidate the transcriptional regulation of...
6.
Dickinson B, Semus H, Montgomery R, Stack C, Latimer P, Lewton S, et al.
Eur J Heart Fail . 2013 Feb; 15(6):650-9. PMID: 23388090
Aims: Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to...
7.
Seto A, Van Rooij E
Eur J Heart Fail . 2012 Jan; 14(2):118-9. PMID: 22253452
No abstract available.
8.
Hullinger T, Montgomery R, Seto A, Dickinson B, Semus H, Lynch J, et al.
Circ Res . 2011 Nov; 110(1):71-81. PMID: 22052914
Rationale: Myocardial infarction (MI) is a leading cause of death worldwide. Because endogenous cardiac repair mechanisms are not sufficient for meaningful tissue regeneration, MI results in loss of cardiac tissue...
9.
Montgomery R, Hullinger T, Semus H, Dickinson B, Seto A, Lynch J, et al.
Circulation . 2011 Sep; 124(14):1537-47. PMID: 21900086
Background: Diastolic dysfunction in response to hypertrophy is a major clinical syndrome with few therapeutic options. MicroRNAs act as negative regulators of gene expression by inhibiting translation or promoting degradation...
10.
Seto A
Int J Biochem Cell Biol . 2010 Mar; 42(8):1298-305. PMID: 20227519
Within the last 15 years, microRNAs (miRNAs) have emerged as powerful regulators of gene expression. Highly conserved, these small RNAs appear to regulate nearly every aspect of eukaryotic biology. Perturbation...