Anindita Gayen
Overview
Explore the profile of Anindita Gayen including associated specialties, affiliations and a list of published articles.
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19
Citations
203
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Recent Articles
1.
Kumar D, Gayen A, Chandra M
ACS Infect Dis
. 2024 Aug;
10(9):3233-3244.
PMID: 39178142
Depending upon nutrient availability, bacteria transit to multiple growth phases. The transition from the active to nongrowing phase results in reduced drug efficacy and, in some cases, even multidrug resistance....
2.
Singh D, Kumar D, Gayen A, Chandra M
J Phys Chem Lett
. 2024 Jul;
15(31):7832-7839.
PMID: 39052610
Multidrug efflux pumps, especially those belonging to the class of resistance-nodulation-division (RND), are the key contributors to the rapidly growing multidrug resistance in Gram-negative bacteria. Understanding the role of efflux...
3.
Kumar D, Gayen A, Chandra M
J Phys Chem B
. 2024 May;
128(20):4911-4921.
PMID: 38736363
To combat surging multidrug-resistant Gram-negative bacterial infections, better strategies to improve the efficacy of existing drugs are critical. Because the dual membrane cell envelope is the first line of defense...
4.
Kumar D, Gayen A, Chandra M
ACS Infect Dis
. 2023 Nov;
9(12):2471-2481.
PMID: 37950691
Survival of foodborne Gram-negative bacteria during osmotic stress often leads to multidrug resistance development. However, despite the concern, how osmoadaptation alters drug penetration across the Gram-negative bacterial cell envelope has...
5.
Lenka S, Singh D, Paul S, Gayen A, Chandra M
ACS Infect Dis
. 2021 Mar;
7(4):733-745.
PMID: 33703881
Probiotic yeast exerts direct probiotic action on pathogenic by trapping them on surfaces and inactivating toxic lipopolysaccharides. Using optical dark-field microscopy, we show that nonpathogenic cells also readily bind probiotic...
6.
Gayen A, Kumar D, Matheshwaran S, Chandra M
Anal Chem
. 2019 Apr;
91(12):7662-7671.
PMID: 30986344
Quantitative evaluation of small molecule permeation and accumulation in Gram-negative bacteria is important for drug development against these bacteria. While these measurements are commonly performed at physiological pH, Escherichia coli...
7.
Gayen A, Leninger M, Traaseth N
Nat Chem Biol
. 2016 Jan;
12(3):141-5.
PMID: 26751516
Secondary active transport proteins play a central role in conferring bacterial multidrug resistance. In this work, we investigated the proton-coupled transport mechanism for the Escherichia coli drug efflux pump EmrE...
8.
Banigan J, Gayen A, Cho M, Traaseth N
J Biol Chem
. 2014 Nov;
290(2):805-14.
PMID: 25406320
Secondary active transporters undergo large conformational changes to facilitate the efflux of substrates across the lipid bilayer. Among the smallest known transport proteins are members of the small multidrug resistance...
9.
Khatun U, Gayen A, Mukhopadhyay C
Glycoconj J
. 2014 Sep;
31(6-7):435-47.
PMID: 25178424
Gangliosides, are glycosphingolipids, present in all vertebrate plasma membranes with particular abundance in nerve cell membrane. Gangliosides can act as portals for antimicrobial peptides, hormones, viruses, lectins, toxins and pathogens....
10.
Cho M, Gayen A, Banigan J, Leninger M, Traaseth N
J Am Chem Soc
. 2014 May;
136(22):8072-80.
PMID: 24856154
EmrE is a multidrug resistance efflux pump with specificity to a wide range of antibiotics and antiseptics. To obtain atomic-scale insight into the attributes of the native state that encodes...