Aniek van der Vaart
Overview
Explore the profile of Aniek van der Vaart including associated specialties, affiliations and a list of published articles.
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10
Citations
317
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0
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Recent Articles
1.
Wolf van der Meer J, Larue A, van der Knaap J, Chalkley G, Sijm A, Beikmohammadi L, et al.
Genes Dev
. 2025 Feb;
39(5-6):401-422.
PMID: 39919828
Pathogenic variants in the ubiquitin-specific protease 7 () gene cause a neurodevelopmental disorder called Hao-Fountain syndrome. However, it remains unclear which of USP7's pleiotropic functions are relevant for neurodevelopment. Here,...
2.
van der Vaart A, Godfrey M, Portegijs V, van den Heuvel S
Sci Adv
. 2020 Jun;
6(21):eaay3823.
PMID: 32494730
SWI/SNF (switch/sucrose nonfermenting) complexes regulate transcription through chromatin remodeling and opposing gene silencing by Polycomb group (PcG) proteins. Genes encoding SWI/SNF components are critical for normal development and frequently mutated...
3.
van der Vaart A, van den Heuvel S
Stem Cell Investig
. 2016 Sep;
3:41.
PMID: 27668248
No abstract available.
4.
van der Vaart A, Rademakers S, Jansen G
PLoS Genet
. 2015 Dec;
11(12):e1005733.
PMID: 26657059
Cilia are sensory organelles present on almost all vertebrate cells. Cilium length is constant, but varies between cell types, indicating that cilium length is regulated. How this is achieved is...
5.
Wilson-Zbinden C, Xavier da Silveira Dos Santos A, Stoffel-Studer I, van der Vaart A, Hofmann K, Reggiori F, et al.
Genetics
. 2014 Dec;
199(2):475-85.
PMID: 25519895
Autophagy is a highly regulated pathway that selectively degrades cellular constituents such as protein aggregates and excessive or damaged organelles. This transport route is characterized by engulfment of the targeted...
6.
Cebollero E, van der Vaart A, Reggiori F
Autophagy
. 2012 Sep;
8(12):1868-70.
PMID: 22992453
Autophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cytoplasmic components. They are generated at the phagophore assembly site (PAS), the phagophore being the precursor structure of these carriers. According...
7.
Cebollero E, van der Vaart A, Zhao M, Rieter E, Klionsky D, Helms J, et al.
Curr Biol
. 2012 Jul;
22(17):1545-53.
PMID: 22771041
Background: The biogenesis of autophagosomes, the hallmark of autophagy, depends on the function of the autophagy-related (Atg) proteins and the generation of phosphatidylinositol-3-phosphate (PtdIns3P) at the phagophore assembly site (PAS),...
8.
van der Vaart A, Reggiori F
Autophagy
. 2010 Aug;
6(6):800-1.
PMID: 20714226
Today, more than 50 years after the discovery of autophagy, the origin of the autophagosomal membranes remains for the most part elusive. Many sources for the lipid bilayers have been...
9.
van der Vaart A, Griffith J, Reggiori F
Mol Biol Cell
. 2010 May;
21(13):2270-84.
PMID: 20444982
The delivery of proteins and organelles to the vacuole by autophagy involves membrane rearrangements that result in the formation of large vesicles called autophagosomes. The mechanism underlying autophagosome biogenesis and...
10.
van der Vaart A, Mari M, Reggiori F
Traffic
. 2007 Nov;
9(3):281-9.
PMID: 17988219
Autophagy is a catabolic process conserved among all eukaryotes essential for the cellular and organismal homeostasis. One of the principal roles of this pathway is to maintain an accurate balance...