Ani Manichaikul
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Explore the profile of Ani Manichaikul including associated specialties, affiliations and a list of published articles.
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183
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10757
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Recent Articles
1.
Guo B, Cai Y, Kim D, Smit R, Wang Z, Iyer K, et al.
medRxiv
. 2025 Mar;
PMID: 40034751
Polygenic risk scores (PRS) hold prognostic value for identifying individuals at higher risk of type 2 diabetes (T2D). However, further characterization is needed to understand the generalizability of T2D PRS...
2.
Nicholas J, Raffield L, Katz D, Nicholas J, Tahir U, Katz D, et al.
Res Sq
. 2025 Feb;
PMID: 39989965
Measures from affinity-proteomics platforms often correlate poorly, challenging interpretation of protein associations with genetic variants (pQTL) and phenotypes. Here, we examined 2,157 proteins measured on both SomaScan 7k and Olink...
3.
Hu X, Webb-Robertson B, Parikh H, Nakayasu E, Onengut-Gumuscu S, Chen W, et al.
Res Sq
. 2025 Feb;
PMID: 39989961
Background: Type 1 diabetes (T1D) is characterized by the autoimmune destruction of the insulin-producing beta cells, and there is no cure yet for the disease. While islet autoantibodies are well-recognized...
4.
Rodriguez A, Yang C, Gan W, Karlinsey K, Zhou B, Rich S, et al.
medRxiv
. 2025 Jan;
PMID: 39830278
Adverse cardiovascular events are emerging with the use of immune checkpoint therapies in oncology. Using datasets in the Trans-Omics for Precision Medicine program (Multi-Ethnic Study of Atherosclerosis, Jackson Heart Study...
5.
Multi-ancestry genome-wide association study reveals novel genetic signals for lung function decline
Patchen B, Zhang J, Gaddis N, Bartz T, Chen J, Debban C, et al.
medRxiv
. 2024 Dec;
PMID: 39649580
Rationale: Accelerated decline in lung function contributes to the development of chronic respiratory disease. Despite evidence for a genetic component, few genetic associations with lung function decline have been identified....
6.
Zhang D, Gao B, Feng Q, Manichaikul A, Peloso G, Tracy R, et al.
HGG Adv
. 2024 Nov;
6(1):100383.
PMID: 39543875
Blood lipid traits are treatable and heritable risk factors for heart disease, a leading cause of mortality worldwide. Although genome-wide association studies (GWASs) have discovered hundreds of variants associated with...
7.
Borda V, Loesch D, Guo B, Laboulaye R, Veliz-Otani D, French J, et al.
Cell Genom
. 2024 Nov;
4(11):100692.
PMID: 39486408
Latin Americans are underrepresented in genetic studies, increasing disparities in personalized genomic medicine. Despite available genetic data from thousands of Latin Americans, accessing and navigating the bureaucratic hurdles for consent...
8.
Kim J, Flack K, Malik V, Manichaikul A, Sakaue S, Luo Y, et al.
Ann Am Thorac Soc
. 2024 Oct;
PMID: 39405163
Rationale: Rheumatoid arthritis (RA) has been implicated in interstitial lung disease (ILD) as majority of studies have been comprised of patients with known RA. However, it remains unclear whether an...
9.
Naik S, Angelini E, Barr R, Allen N, Bertoni A, Hoffman E, et al.
Proc IEEE Int Symp Biomed Imaging
. 2024 Oct;
2024.
PMID: 39398280
High-resolution full lung CT scans now enable the detailed segmentation of airway trees up to the 6th branching generation. The airway binary masks display very complex tree structures that may...
10.
Moll M, Pratte K, Debban C, Liu C, Belinsky S, Picchi M, et al.
Sci Rep
. 2024 Sep;
14(1):20618.
PMID: 39232179
Protein biomarkers are associated with mortality in cardiovascular disease, but their effect on predicting respiratory and all-cause mortality is not clear. We tested whether a protein risk score (protRS) can...