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Andrii Domanskyi

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Articles 41
Citations 958
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Recent Articles
1.
Er S, Parkkinen I, Trepczyk K, Seelbach A, Pasculli M, De Lorenzo F, et al.
Eur J Pharm Sci . 2025 Feb; 208:107048. PMID: 39988264
Failures in protein homeostasis are linked to Parkinson's disease (PD) and other neurodegenerative diseases. Lewy bodies, proteinaceous inclusions rich in phosphorylated alpha-synuclein are a hallmark of PD. Glial cell line-derived...
2.
Wei H, Vuorenpaa A, Laurila J, Domanskyi A, Koivisto A, Pertovaara A
Brain Res Bull . 2024 Sep; 217:111089. PMID: 39341510
Here we assess whether neuropathic pain hypersensitivity is attenuated by spinal administration of the imidazoline I-receptor agonist LNP599 and whether the attenuation involves co-activation of α-adrenoceptors. Spared nerve injury (SNI)...
3.
Juuri E, Tikka P, Domanskyi A, Corfe I, Morita W, McKinnon P, et al.
Front Physiol . 2022 May; 13:877565. PMID: 35574464
Ptch receptors 1 and 2 mediate Hedgehog signaling pivotal for organ development and homeostasis. In contrast to embryonic lethal phenotype, mice display no effect on gross phenotype. In this brief...
4.
Lampinen R, Belaya I, Saveleva L, Liddell J, Rait D, Huuskonen M, et al.
Neurobiol Dis . 2022 May; 170:105753. PMID: 35569719
Under physiological conditions in vivo astrocytes internalize and degrade neuronal mitochondria in a process called transmitophagy. Mitophagy is widely reported to be impaired in neurodegeneration but it is unknown whether...
5.
Rantataro S, Parkkinen I, Pande I, Domanskyi A, Airavaara M, Peltola E, et al.
Acta Biomater . 2022 Apr; 146:235-247. PMID: 35487425
Vertically aligned carbon nanofibers (VACNFs) are promising material candidates for neural biosensors due to their ability to detect neurotransmitters in physiological concentrations. However, the expected high rigidity of CNFs could...
6.
Hlushchuk I, Barut J, Airavaara M, Luk K, Domanskyi A, Chmielarz P
Biomolecules . 2022 Apr; 12(4). PMID: 35454152
There are several links between insulin resistance and neurodegenerative disorders such as Parkinson's disease. However, the direct influence of insulin signaling on abnormal α-synuclein accumulation-a hallmark of Parkinson's disease-remains poorly...
7.
Domanskyi A, Parlato R
Antioxidants (Basel) . 2022 Mar; 11(3). PMID: 35326154
Oxidative stress is typically reported in neurodegenerative diseases [...].
8.
Prebble D, Er S, Hlushchuk I, Domanskyi A, Airavaara M, Ekins M, et al.
Bioorg Med Chem Lett . 2022 Mar; 64:128677. PMID: 35301136
Preventing the aggregation of certain amyloid proteins has the potential to slow down the progression of diseases like Alzheimer's, Parkinson's, and type 2 diabetes mellitus. During a high-throughput screen of...
9.
Holland D, Prebble D, Er S, Hayton J, Robertson L, Avery V, et al.
J Nat Prod . 2022 Jan; 85(2):441-452. PMID: 35050597
Seven new polyaromatic bis-spiroketal-containing butenolides, the prunolides D-I (-) and -prunolide C (), a new dibrominated β-carboline sulfamate named pityriacitrin C (), alongside the known prunolides A-C (-) were isolated...
10.
Kujawska M, Domanskyi A, Kreiner G
Front Cell Neurosci . 2021 Sep; 15:754051. PMID: 34588959
No abstract available.