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Andrew Savidge

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Zhang H, Sim G, Kehling A, Adhav V, Savidge A, Pastore B, et al.
Cell Rep . 2024 Oct; 43(10):114806. PMID: 39368090
TinyRNAs (tyRNAs) are ≤17-nt guide RNAs associated with Argonaute proteins (AGOs), and certain 14-nt cleavage-inducing tyRNAs (cityRNAs) catalytically activate human Argonaute3 (AGO3). We present the crystal structure of AGO3 in...