Andrew S Goldstein
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Explore the profile of Andrew S Goldstein including associated specialties, affiliations and a list of published articles.
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52
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1871
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Recent Articles
1.
Drian A, Goldstein S, Kim N, Goldstein A, Hartzell-Cushanick R, Yee A, et al.
J Sex Med
. 2024 Mar;
21(5):479-493.
PMID: 38521973
Background: Neuroproliferative vestibulodynia (NPV), a provoked genital pain characterized by severe allodynia and hyperalgesia, is confirmed in excised vestibular tissue by immunohistochemical staining (>8 CD117-positive immunostained cells/100× microscopic field) rather...
2.
Rat Model of Type 2 Diabetes Mellitus Recapitulates Human Disease in the Anterior Segment of the Eye
Wang C, Skeie J, Allamargot C, Goldstein A, Nishimura D, Huffman J, et al.
Am J Pathol
. 2024 Feb;
194(6):1090-1105.
PMID: 38403162
Changes in the anterior segment of the eye due to type 2 diabetes mellitus (T2DM) are not well-characterized, in part due to the lack of a reliable animal model. This...
3.
Bernard M, Goldstein A
Cancer Res
. 2024 Feb;
84(9):1382-1383.
PMID: 38330100
Over the past decade, studies have increasingly shed light on a reciprocal relationship between cellular metabolism and cell fate, meaning that a cell's lineage both drives and is governed by...
4.
Giafaglione J, Crowell P, Delcourt A, Hashimoto T, Ha S, Atmakuri A, et al.
Nat Cell Biol
. 2023 Dec;
25(12):1821-1832.
PMID: 38049604
Lineage transitions are a central feature of prostate development, tumourigenesis and treatment resistance. While epigenetic changes are well known to drive prostate lineage transitions, it remains unclear how upstream metabolic...
5.
Wang C, Clemot M, Hashimoto T, Diaz J, Goins L, Goldstein A, et al.
Sci Signal
. 2023 Nov;
16(810):eabo5213.
PMID: 37934809
Dysregulated Notch signaling is a common feature of cancer; however, its effects on tumor initiation and progression are highly variable, with Notch having either oncogenic or tumor-suppressive functions in various...
6.
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
Crowell P, Giafaglione J, Jones A, Nunley N, Hashimoto T, Delcourt A, et al.
Cell Rep
. 2023 Oct;
42(10):113221.
PMID: 37815914
Advanced prostate cancers are treated with therapies targeting the androgen receptor (AR) signaling pathway. While many tumors initially respond to AR inhibition, nearly all develop resistance. It is critical to...
7.
Bernard M, Smith C, Goldstein A
J Pathol
. 2023 Sep;
261(4):375-377.
PMID: 37775958
Single-cell RNA sequencing studies in the human prostate have defined a population of epithelial cells with transcriptional similarities to club cells in the lung. However, the localization of club-like cells...
8.
Fox J, Hashimoto T, Navarro H, Garcia A, Shou B, Goldstein A
Aging (Albany NY)
. 2023 May;
15(9):3356-3380.
PMID: 37179121
Aging is a significant risk factor for disease in several tissues, including the prostate. Defining the kinetics of age-related changes in these tissues is critical for identifying regulators of aging...
9.
Payne M, Ho S, Hashimoto T, Imboden S, Diaz J, Lee B, et al.
Biotechnol J
. 2023 Mar;
18(6):e2200434.
PMID: 36905340
3D cancer spheroids represent a highly promising model for study of cancer progression and therapeutic development. Wide-scale adoption of cancer spheroids, however, remains a challenge due to the lack of...
10.
Freeland J, Crowell P, Giafaglione J, Boutros P, Goldstein A
Cancer Lett
. 2021 May;
515:28-35.
PMID: 34052326
Many organs experience a loss of tissue mass and a decline in regenerative capacity during aging. In contrast, the prostate continues to grow in volume. In fact, age is the...