Andrew R Gorringe
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Explore the profile of Andrew R Gorringe including associated specialties, affiliations and a list of published articles.
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28
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645
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Recent Articles
11.
Vaughan T, Pratt C, Sealey K, Preston A, Fry N, Gorringe A
Microbiology (Reading)
. 2014 Jul;
160(Pt 9):2030-2044.
PMID: 25028460
The fimbriae of Bordetella pertussis are required for colonization of the human respiratory tract. Two serologically distinct fimbrial subunits, Fim2 and Fim3, considered important vaccine components for many years, are...
12.
Hallander H, Advani A, Alexander F, Gustafsson L, Ljungman M, Pratt C, et al.
Clin Vaccine Immunol
. 2013 Dec;
21(2):165-73.
PMID: 24307240
Bordetella pertussis fimbriae (Fim2 and Fim3) are components of a five-component acellular pertussis vaccine (diphtheria-tetanus-acellular pertussis vaccine [DTaP5]), and antibody responses to fimbriae have been associated with protection. We analyzed...
13.
Alexander F, Matheson M, Fry N, Labram B, Gorringe A
Clin Vaccine Immunol
. 2012 Sep;
19(11):1776-83.
PMID: 22956654
Bordetella pertussis expresses two serologically distinct fimbriae (Fim2 and Fim3) which are included in the Sanofi Pasteur 5-component acellular pertussis vaccine, and antibody responses to these antigens have been shown...
14.
Gorringe A, Pajon R
Hum Vaccin Immunother
. 2012 Mar;
8(2):174-83.
PMID: 22426368
Serogroup B meningococcal (MenB) disease remains a serious public health problem for which a cross-protective vaccine effective against a wide range of MenB isolates has not been available. Novartis Vaccines...
15.
Noinaj N, Easley N, Oke M, Mizuno N, Gumbart J, Boura E, et al.
Nature
. 2012 Feb;
483(7387):53-8.
PMID: 22327295
Neisseria are obligate human pathogens causing bacterial meningitis, septicaemia and gonorrhoea. Neisseria require iron for survival and can extract it directly from human transferrin for transport across the outer membrane....
16.
Green L, Monk P, Partridge L, Morris P, Gorringe A, Read R
Infect Immun
. 2011 Apr;
79(6):2241-9.
PMID: 21464080
The tetraspanins are a superfamily of transmembrane proteins with diverse functions and can form extended microdomains within the plasma membrane in conjunction with partner proteins, which probably includes receptors for...
17.
Evans C, Pratt C, Matheson M, Vaughan T, Findlow J, Borrow R, et al.
Clin Infect Dis
. 2010 Dec;
52(1):70-7.
PMID: 21148522
Background: Natural immunity to Neisseria meningitidis may result from nasopharyngeal carriage of closely related commensals, such as Neisseria lactamica. Methods: We enrolled 61 students with no current carriage of Neisseria...
18.
Gorringe A, van Alphen L
Hum Vaccin
. 2009 Aug;
5(2):53-6.
PMID: 19684470
The report describes developments in meningococcal disease vaccines presented at the 16th International Pathogenic Neisseria Conference, Rotterdam, 7-12 September 2008. Great progress has been made by the Meningitis Vaccine Project...
19.
Gorringe A, Taylor S, Brookes C, Matheson M, Finney M, Kerr M, et al.
Clin Vaccine Immunol
. 2009 Jun;
16(8):1113-20.
PMID: 19553555
Natural immunity to meningococcal disease in young children is associated epidemiologically with carriage of commensal Neisseria species, including Neisseria lactamica. We have previously demonstrated that outer membrane vesicles (OMVs) from...
20.
Li M, Chow N, Sinha S, Halliwell D, Finney M, Gorringe A, et al.
Med Microbiol Immunol
. 2008 Dec;
198(1):57-67.
PMID: 19050914
We sought to determine whether NMB1966, encoding a putative ABC transporter, has a role in pathogenesis. Compared to its isogenic wild-type parent strain Neisseria meningitidis MC58, the NMB1966 knockout mutant...