Adam P Dale
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Explore the profile of Adam P Dale including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
239
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Recent Articles
1.
Theodosiou A, Bogaert D, Cleary D, Dale A, Gbesemete D, Guy J, et al.
Lancet Microbe
. 2025 Feb;
:100986.
PMID: 39986292
Background: The infant respiratory microbiome is derived largely from the mother and is associated with downstream health and disease. Manipulating maternal respiratory flora peripartum to influence the infant microbiome has...
2.
Dale A, Theodosiou A, Gbesemete D, Guy J, Jones E, Hill A, et al.
Lancet Microbe
. 2022 Dec;
3(12):e931-e943.
PMID: 36462524
Background: Pharyngeal colonisation by the commensal bacterium Neisseria lactamica inhibits colonisation by Neisseria meningitidis and has an inverse epidemiological association with meningococcal disease. The mechanisms that underpin this relationship are...
3.
Theodosiou A, Laver J, Dale A, Cleary D, Jones C, Read R
BMJ Open
. 2022 May;
12(5):e056081.
PMID: 35584870
Introduction: Infant upper respiratory microbiota are derived partly from the maternal respiratory tract, and certain microbiota are associated with altered risk of infections and respiratory disease. is a common pharyngeal...
4.
Dale A, Gbesemete D, Read R, Laver J
Methods Mol Biol
. 2021 Nov;
2414:387-404.
PMID: 34784048
Neisseria lactamica is a nonpathogenic commensal of the human upper respiratory tract that has been associated with protection against N. meningitidis colonization and disease. We have previously utilized the N....
5.
Laver J, Gbesemete D, Dale A, Pounce Z, Webb C, Roche E, et al.
Sci Transl Med
. 2021 Jul;
13(601).
PMID: 34233953
The human nasopharynx contains a stable microbial ecosystem of commensal and potentially pathogenic bacteria, which can elicit protective primary and secondary immune responses. Experimental intranasal infection of human adults with...
6.
Pandey A, Cleary D, Laver J, Gorringe A, Deasy A, Dale A, et al.
Nat Commun
. 2018 Nov;
9(1):4753.
PMID: 30420631
Neisseria lactamica is a harmless coloniser of the infant respiratory tract, and has a mutually-excluding relationship with the pathogen Neisseria meningitidis. Here we report controlled human infection with genomically-defined N....
7.
Dale A, Pandey A, Hesp R, Belogiannis K, Laver J, Shone C, et al.
J Infect
. 2018 Nov;
77(6):534-543.
PMID: 30391630
Objectives: Escherichia coli is the leading cause of bacteraemia. In an era of emerging multi-drug-resistant strains, development of effective preventative strategies will be informed by knowledge of strain diversity associated...
8.
Dale A, Woodford N
J Infect
. 2015 Sep;
71(6):615-26.
PMID: 26409905
Extra-intestinal pathogenic Escherichia coli (ExPEC) have a complex phylogeny, broad virulence factor (VF) armament and significant genomic plasticity, and are associated with a spectrum of host infective syndromes ranging from...
9.
Deasy A, Guccione E, Dale A, Andrews N, Evans C, Bennett J, et al.
Clin Infect Dis
. 2015 Mar;
60(10):1512-20.
PMID: 25814628
Background: Herd protection by meningococcal vaccines is conferred by population-level reduction of meningococcal nasopharyngeal colonization. Given the inverse epidemiological association between colonization by commensal Neisseria lactamica and meningococcal disease, we...
10.
Dale A, Khan R, Mathew A, Hersey N, Peck R, Lee F, et al.
Cardiovasc Intervent Radiol
. 2015 Mar;
38(5):1244-51.
PMID: 25762487
Purpose: PTC and stenting procedures are associated with significant risks including life-threatening haemorrhage, sepsis, renal failure and high mortality rates. PTC tract closure methods are utilised to reduce haemorrhagic complications...