Andrew P Feranchak
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Explore the profile of Andrew P Feranchak including associated specialties, affiliations and a list of published articles.
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30
Citations
875
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Recent Articles
1.
Kulkarni S, Li Q, Singhi A, Liu S, Monga S, Feranchak A
Am J Physiol Gastrointest Liver Physiol
. 2023 May;
325(2):G122-G134.
PMID: 37219012
Expression of transmembrane protein 16 A (TMEM16A), a calcium activated chloride channel, is elevated in some human cancers and impacts tumor cell proliferation, metastasis, and patient outcome. Evidence presented here...
2.
Truong J, Li J, Li Q, Pachura K, Rao A, Gumber S, et al.
JCI Insight
. 2023 Feb;
8(6).
PMID: 36787187
The pronounced choleretic properties of 24-norUrsodeoxycholic acid (norUDCA) to induce bicarbonate-rich bile secretion have been attributed to its ability to undergo cholehepatic shunting. The goal of this study was to...
3.
Shcheynikov N, Boggs K, Green A, Feranchak A
Hepatology
. 2022 Apr;
76(5):1248-1258.
PMID: 35445421
Background And Aims: Chloride (Cl ) channels in the apical membrane of biliary epithelial cells (BECs), also known as cholangiocytes, provide the driving force for biliary secretion. Although two Cl...
4.
Florentino R, Li Q, Coard M, Haep N, Motomura T, Diaz-Aragon R, et al.
Hepatol Commun
. 2022 Mar;
6(7):1561-1573.
PMID: 35289126
The initial creation of human-induced pluripotent stem cells (iPSCs) set the foundation for the future of regenerative medicine. Human iPSCs can be differentiated into a variety of cell types in...
5.
Dutta A, Boggs K, Khimji A, Getachew Y, Wang Y, Kresge C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2020 Feb;
318(4):G763-G771.
PMID: 32090602
TMEM16A is a Ca-activated Cl channel in the apical membrane of biliary epithelial cells, known as cholangiocytes, which contributes importantly to ductular bile formation. Whereas cholangiocyte TMEM16A activity is regulated...
6.
Li Q, Dutta A, Kresge C, Bugde A, Feranchak A
Hepatology
. 2018 Jan;
68(1):187-199.
PMID: 29360145
Conclusion: Bile acids stimulate Cl secretion in mouse and human biliary cells through activation of membrane TMEM16A channels in a process regulated by extracellular ATP and [Ca ] . These...
7.
8.
Dutta A, Khimji A, Liu S, Karamysheva Z, Fujita A, Kresge C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2015 Nov;
310(1):G34-42.
PMID: 26542395
TMEM16A is a newly identified Ca(2+)-activated Cl(-) channel in biliary epithelial cells (BECs) that is important in biliary secretion. While extracellular ATP stimulates TMEM16A via binding P2 receptors and increasing...
9.
Li Q, Kresge C, Bugde A, Lamphere M, Park J, Feranchak A
Hepatology
. 2015 Oct;
63(2):538-49.
PMID: 26475057
Unlabelled: Intrahepatic biliary epithelial cells (BECs), also known as cholangiocytes, modulate the volume and composition of bile through the regulation of secretion and absorption. While mechanosensitive Cl(-) efflux has been...
10.
Geisler J, Corbin K, Li Q, Feranchak A, Nunemaker C, Li C
Endocrinology
. 2012 Dec;
154(2):675-84.
PMID: 23254199
Extracellular ATP plays a critical role in regulating insulin secretion in pancreatic β cells. The ATP released from insulin secretory vesicles has been proposed to be a major source of...