Andrew P Feranchak
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Explore the profile of Andrew P Feranchak including associated specialties, affiliations and a list of published articles.
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30
Citations
875
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Recent Articles
11.
Dutta A, Woo K, Khimji A, Kresge C, Feranchak A
Am J Physiol Gastrointest Liver Physiol
. 2012 Oct;
304(1):G87-98.
PMID: 23104560
Bile formation by the liver is initiated by canalicular transport at the hepatocyte membrane, leading to an increase in ductular bile flow. Thus, bile duct epithelial cells (cholangiocytes), which contribute...
12.
Mendoza J, Schmidt A, Li Q, Nuvaga E, Barrett T, Bridges R, et al.
Cell
. 2012 Jan;
148(1-2):164-74.
PMID: 22265409
Misfolding of ΔF508 cystic fibrosis (CF) transmembrane conductance regulator (CFTR) underlies pathology in most CF patients. F508 resides in the first nucleotide-binding domain (NBD1) of CFTR near a predicted interface...
13.
Sathe M, Woo K, Kresge C, Bugde A, Luby-Phelps K, Lewis M, et al.
J Biol Chem
. 2011 May;
286(28):25363-76.
PMID: 21613220
ATP in bile is a potent secretogogue, stimulating biliary epithelial cell (BEC) secretion through binding apical purinergic receptors. In response to mechanosensitive stimuli, BECs release ATP into bile, although the...
14.
Dutta A, Khimji A, Kresge C, Bugde A, Dougherty M, Esser V, et al.
J Biol Chem
. 2010 Nov;
286(1):766-76.
PMID: 21041307
Cl(-) channels in the apical membrane of biliary epithelial cells (BECs) provide the driving force for ductular bile formation. Although a cystic fibrosis transmembrane conductance regulator has been identified in...
15.
Woo K, Sathe M, Kresge C, Esser V, Ueno Y, Venter J, et al.
Hepatology
. 2010 Sep;
52(5):1819-28.
PMID: 20827720
Unlabelled: Adenosine triphosphate (ATP) is released from cholangiocytes into bile and is a potent secretogogue by increasing intracellular Ca²(+) and stimulating fluid and electrolyte secretion via binding purinergic (P2) receptors...
16.
Dutta A, Khimji A, Sathe M, Kresge C, Parameswara V, Esser V, et al.
Am J Physiol Gastrointest Liver Physiol
. 2010 May;
297(5):G1009-18.
PMID: 20501432
In the liver, adenosine triphosphate (ATP) is an extracellular signaling molecule that is released into bile and stimulates a biliary epithelial cell secretory response via engagement of apical P2 receptors....
17.
Feranchak A, Lewis M, Kresge C, Sathe M, Bugde A, Luby-Phelps K, et al.
J Biol Chem
. 2010 Jan;
285(11):8138-47.
PMID: 20071341
Extracellular ATP represents an important autocrine/paracrine signaling molecule within the liver. The mechanisms responsible for ATP release are unknown, and alternative pathways have been proposed, including either conductive ATP movement...
18.
Simpson L, Burdine L, Dutta A, Feranchak A, Kodadek T
J Am Chem Soc
. 2009 Apr;
131(16):5760-2.
PMID: 19351156
Bacterial toxin-mediated diarrheal disease is a major cause of morbidity and mortality worldwide. In this work we designed an on-bead library of protease-resistant, acid-stable peptoid molecules and screened for high...
19.
Dutta A, Woo K, Brian Doctor R, Fitz J, Feranchak A
Am J Physiol Gastrointest Liver Physiol
. 2008 Sep;
295(5):G1004-15.
PMID: 18787062
Extracellular ATP regulates bile formation by binding to P2 receptors on cholangiocytes and stimulating transepithelial Cl(-) secretion. However, the specific signaling pathways linking receptor binding to Cl(-) channel activation are...
20.
Stallings V, Stark L, Robinson K, Feranchak A, Quinton H
J Am Diet Assoc
. 2008 Apr;
108(5):832-9.
PMID: 18442507
The Cystic Fibrosis Foundation established a process of systematic review of evidence to inform the development of clinical care guidelines and encourage evidence-based practice. The Subcommittee on Growth and Nutrition...