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Andrew M Tilston-Lunel

Explore the profile of Andrew M Tilston-Lunel including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 109
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Recent Articles
1.
Ning B, Tilston-Lunel A, Simonetti J, Hicks-Berthet J, Matschulat A, Pfefferkorn R, et al.
J Exp Clin Cancer Res . 2023 May; 42(1):116. PMID: 37150829
Background: Bronchial premalignant lesions (PMLs) are composed primarily of cells resembling basal epithelial cells of the airways, which through poorly understood mechanisms have the potential to progress to lung squamous...
2.
Tilston-Lunel A, Varelas X
Curr Top Dev Biol . 2023 Apr; 154:285-315. PMID: 37100521
The respiratory system is composed of a multitude of cells that organize to form complex branched airways that end in alveoli, which respectively function to guide air flow and mediate...
3.
Kern J, Tilston-Lunel A, Federico A, Ning B, Mueller A, Peppler G, et al.
Nat Commun . 2022 Nov; 13(1):7198. PMID: 36443313
Basal-like breast cancers, an aggressive breast cancer subtype that has poor treatment options, are thought to arise from luminal mammary epithelial cells that undergo basal plasticity through poorly understood mechanisms....
4.
Alysandratos K, Russo S, Petcherski A, Taddeo E, Acin-Perez R, Villacorta-Martin C, et al.
Cell Rep . 2021 Sep; 36(9):109636. PMID: 34469722
Alveolar epithelial type 2 cell (AEC2) dysfunction is implicated in the pathogenesis of adult and pediatric interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF); however, identification of disease-initiating mechanisms...
5.
Chan S, Smith E, Gao Y, Kwan J, Blum B, Tilston-Lunel A, et al.
Front Cell Dev Biol . 2021 Jan; 8:608044. PMID: 33490071
G Protein Suppressor 2 (GPS2) is a multifunctional protein that exerts important roles in inflammation and metabolism in adipose, liver, and immune cells. GPS2 has recently been identified as a...
6.
Kingston N, Tilston-Lunel A, Hicks-Berthet J, Varelas X
Methods Mol Biol . 2018 Dec; 1893:107-113. PMID: 30565129
The transcriptional coactivator with PDZ-binding motif (TAZ), which is encoded by the WWTR1 gene, is a key transcriptional effector of the Hippo signaling pathway. TAZ function has been implicated in...
7.
Gunn-Moore F, Tilston-Lunel A, Reynolds P
Genes (Basel) . 2016 Jul; 7(7). PMID: 27438856
Genome sequencing is now a common procedure, but prior to this, screening experiments using protein baits was one of the routinely used methods that, occasionally, allowed the identification of new...
8.
Tilston-Lunel A, Haley K, Schlecht N, Wang Y, Chatterton A, Moleirinho S, et al.
J Mol Cell Biol . 2016 May; 8(5):439-455. PMID: 27190314
Crumbs 3 (CRB3) is a component of epithelial junctions, which has been implicated in apical-basal polarity, apical identity, apical stability, cell adhesion, and cell growth. CRB3 undergoes alternative splicing to...
9.
Moleirinho S, Patrick C, Tilston-Lunel A, Higginson J, Angus L, Antkowiak M, et al.
PLoS One . 2013 Apr; 8(4):e60028. PMID: 23593160
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results...