Michael B Prystowsky
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Explore the profile of Michael B Prystowsky including associated specialties, affiliations and a list of published articles.
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79
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1563
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Recent Articles
1.
Hu E, An J, Gersten A, Wu N, Kawachi N, Zhu J, et al.
Front Oncol
. 2025 Mar;
15:1539782.
PMID: 40046621
The integration of viral DNA into the human genome is a critical event in the pathogenesis of various cancers. This process leads to genomic instability, disrupts cellular regulatory mechanisms, and...
2.
Smith K, Zubair R, Smith R, Augustine S, Schlecht N, Ow T, et al.
Biomedicines
. 2024 Nov;
12(11).
PMID: 39595048
Background: Novel ZNF genes, such as ZNF671, that are located on chromosome 19q13 are known to be hypermethylated at a high frequency in HNSCC as well as in other epithelial...
3.
Li D, Lopez A, Shrivastava N, Chan W, Thomas C, Burk R, et al.
Oral Oncol
. 2024 Oct;
159:107069.
PMID: 39423550
Evasion of apoptosis promotes tumor survival and contributes to resistance to cancer therapeutics in head and neck squamous cell carcinoma (HNSCC). Our recent work has demonstrated that HNSCC's highly express...
4.
Ow T, Mehta V, Li D, Thomas C, Shrivastava N, Kawachi N, et al.
Laryngoscope
. 2024 Jan;
134(6):2748-2756.
PMID: 38288866
Objective: To establish and characterize a diverse library of head and neck squamous cell cancer (HNSCC) cultures using conditional reprogramming (CR). Methods: Patients enrolled on an IRB-approved protocol to generate...
5.
Pearson P, Smith K, Sood N, Chia E, Follett A, Prystowsky M, et al.
J Otolaryngol Head Neck Surg
. 2023 May;
52(1):41.
PMID: 37254212
Background: Krüppel-type zinc finger protein genes located on chromosome 19q13 are aberrantly hypermethylated with high frequency in all anatomic sub-sites of head and neck cancers as well as other epithelial...
6.
Shrivastava N, Chavez C, Li D, Mehta V, Thomas C, Fulcher C, et al.
Cancers (Basel)
. 2023 Apr;
15(7).
PMID: 37046664
Purpose: HPV(-) OCSCC resists radiation treatment. The gene, encoding p16INK4A, is commonly disrupted in OCSCC. p16 inhibits CDK4/CDK6, leading to cell cycle arrest, but the biological sequelae of CDK4/6 inhibition...
7.
Li D, Thomas C, Shrivastava N, Gersten A, Gadsden N, Schlecht N, et al.
J Med Virol
. 2022 Dec;
95(2):e28388.
PMID: 36477880
Most laboratory models of head and neck squamous cell cancer (HNSCC) rely on established immortalized cell lines, which carry inherent bias due to selection and clonality. We established a robust...
8.
Ren Z, Liang H, Galbo Jr P, Dharmaratne M, Kulkarni A, Fard A, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(8).
PMID: 35193955
In search of redox mechanisms in breast cancer, we uncovered a striking role for glutathione peroxidase 2 (GPx2) in oncogenic signaling and patient survival. GPx2 loss stimulates malignant progression due...
9.
Prystowsky M, Cadoff E, Lo Y, Hebert T, Steinberg J
Acad Pathol
. 2021 Nov;
8:23742895211052885.
PMID: 34722866
From our initial screening of applications, we assess that the 10% to 15% of applicants whom we will interview are all academically qualified to complete our residency training program. This...
10.
Ponduri A, Liao D, Schlecht N, Rosenblatt G, Prystowsky M, Kabarriti R, et al.
J Natl Compr Canc Netw
. 2021 Sep;
:1-7.
PMID: 34555804
Background: Nonadherence to NCCN Guidelines during time from surgery to postoperative radiotherapy (S-PORT) can alter survival outcomes in head and neck squamous cell carcinomna (HNSCC). There is a need to...