Andrew J Mannes
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Explore the profile of Andrew J Mannes including associated specialties, affiliations and a list of published articles.
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60
Citations
1355
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Recent Articles
1.
Sapio M, King D, Maric D, Shah S, Talbot T, Manalo A, et al.
J Pain
. 2025 Mar;
:105359.
PMID: 40057214
Background autofluorescence is enhanced in human tissue relative to small animals and presents a barrier to fully realizing the potential of novel multiplex methods in human studies. In particular, lipofuscin...
2.
Iadarola M, Burbelo P, Sapio M, Mannes A
Pain
. 2024 Oct;
165(11):2393-2395.
PMID: 39451111
No abstract available.
3.
Staedtler E, Sapio M, King D, Maric D, Ghetti A, Mannes A, et al.
Cell Rep Med
. 2024 Oct;
5(10):101788.
PMID: 39413733
The shortfall in new analgesic agents is a major impediment to reducing reliance on opioid medications for control of severe pain. In both animals and man, attenuating nociceptive transmission from...
4.
Sapio M, Staedtler E, King D, Maric D, Jahanipour J, Ghetti A, et al.
Pain
. 2024 May;
165(10):2323-2343.
PMID: 38691673
Adenosine receptors are a family of purinergic G protein-coupled receptors that are widely distributed in bodily organs and in the peripheral and central nervous systems. Recently, antihyperalgesic actions have been...
5.
Iadarola M, Sapio M, Loydpierson A, Mervis C, Fehrenbacher J, Vasko M, et al.
JCI Insight
. 2024 Jan;
9(4).
PMID: 38261410
Genetic modifications leading to pain insensitivity phenotypes, while rare, provide invaluable insights into the molecular biology of pain and reveal targets for analgesic drugs. Pain insensitivity typically results from Mendelian...
6.
Sapio M, King D, Staedtler E, Maric D, Jahanipour J, Kurochkina N, et al.
Exp Neurol
. 2023 Oct;
370:114552.
PMID: 37793538
Inherited painless neuropathies arise due to genetic insults that either block the normal signaling of or destroy the sensory afferent neurons in the dorsal root ganglion (DRG) responsible for transducing...
7.
Grant P, Caneris O, Gonzalez R, Iadarola M, Sapio M, Mannes A, et al.
Pain Med
. 2023 Mar;
24(9):1122-1123.
PMID: 36975616
No abstract available.
8.
Domenichiello A, Wilhite B, Nara P, Pitcher M, Keyes G, Mannes A, et al.
Prostaglandins Leukot Essent Fatty Acids
. 2022 Nov;
187:102512.
PMID: 36347090
Clinical studies have demonstrated that decreasing linoleic acid (LA) while increasing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in diets evokes an analgesic effect in headache sufferers. We utilized a...
9.
Pritchard W, Karanian J, Jung C, Bakhutashvili I, Reed S, Starost M, et al.
Sci Transl Med
. 2022 Oct;
14(666):eabm8351.
PMID: 36223450
The COVID-19 pandemic demonstrated the need for inexpensive, easy-to-use, rapidly mass-produced resuscitation devices that could be quickly distributed in areas of critical need. In-line miniature ventilators based on principles of...
10.
Ma W, Sapio M, Manalo A, Maric D, Dougherty M, Goto T, et al.
Front Mol Neurosci
. 2022 Jul;
15:926596.
PMID: 35875671
Primary afferent neurons of the dorsal root ganglia (DRG) transduce peripheral nociceptive signals and transmit them to the spinal cord. These neurons also mediate analgesic control of the nociceptive inputs,...