Michael J Iadarola
Overview
Explore the profile of Michael J Iadarola including associated specialties, affiliations and a list of published articles.
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132
Citations
3602
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Recent Articles
1.
Sapio M, King D, Maric D, Shah S, Talbot T, Manalo A, et al.
J Pain
. 2025 Mar;
:105359.
PMID: 40057214
Background autofluorescence is enhanced in human tissue relative to small animals and presents a barrier to fully realizing the potential of novel multiplex methods in human studies. In particular, lipofuscin...
2.
Iadarola M, Sapio M, Burbelo P
Pain
. 2025 Feb;
166(3):473-474.
PMID: 39928725
No abstract available.
3.
Iadarola M, Burbelo P, Sapio M, Mannes A
Pain
. 2024 Oct;
165(11):2393-2395.
PMID: 39451111
No abstract available.
4.
Staedtler E, Sapio M, King D, Maric D, Ghetti A, Mannes A, et al.
Cell Rep Med
. 2024 Oct;
5(10):101788.
PMID: 39413733
The shortfall in new analgesic agents is a major impediment to reducing reliance on opioid medications for control of severe pain. In both animals and man, attenuating nociceptive transmission from...
5.
Sapio M, Staedtler E, King D, Maric D, Jahanipour J, Ghetti A, et al.
Pain
. 2024 May;
165(10):2323-2343.
PMID: 38691673
Adenosine receptors are a family of purinergic G protein-coupled receptors that are widely distributed in bodily organs and in the peripheral and central nervous systems. Recently, antihyperalgesic actions have been...
6.
Koivisto A, Voets T, Iadarola M, Szallasi A
Curr Opin Pharmacol
. 2024 Mar;
75:102447.
PMID: 38471384
Several decades of research support the involvement of transient receptor potential (TRP) channels in nociception. Despite the disappointments of early TRPV1 antagonist programs, the TRP family remains a promising therapeutic...
7.
Iadarola M, Sapio M, Loydpierson A, Mervis C, Fehrenbacher J, Vasko M, et al.
JCI Insight
. 2024 Jan;
9(4).
PMID: 38261410
Genetic modifications leading to pain insensitivity phenotypes, while rare, provide invaluable insights into the molecular biology of pain and reveal targets for analgesic drugs. Pain insensitivity typically results from Mendelian...
8.
Sapio M, King D, Staedtler E, Maric D, Jahanipour J, Kurochkina N, et al.
Exp Neurol
. 2023 Oct;
370:114552.
PMID: 37793538
Inherited painless neuropathies arise due to genetic insults that either block the normal signaling of or destroy the sensory afferent neurons in the dorsal root ganglion (DRG) responsible for transducing...
9.
Kurochkina N, Sapio M, Iadarola M, Hall B, Kulkarni A
bioRxiv
. 2023 Jul;
PMID: 37502949
Filament systems are comprised of fibrous and globular cytoskeletal proteins and are key elements regulating cell shape, rigidity, and dynamics. The cellular localization and assembly of neurofilaments depend on phosphorylation...
10.
Burbelo P, Ji Y, Iadarola M
Biosensors (Basel)
. 2023 Mar;
13(3).
PMID: 36979515
Antibody measurements play a central role in the diagnosis of many autoimmune and infectious diseases. One antibody detection technology, Luciferase Immunoprecipitation Systems (LIPS), utilizes genetically encoded recombinant luciferase antigen fusion...