Andrew J Grierson
Overview
Explore the profile of Andrew J Grierson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
2365
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bauer C, Webster C, Shaw A, Kok J, Castelli L, Lin Y, et al.
Front Cell Neurosci
. 2023 Jan;
16:1061559.
PMID: 36619668
Disruption to protein homeostasis caused by lysosomal dysfunction and associated impairment of autophagy is a prominent pathology in amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). The most common genetic cause...
2.
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD
Bauer C, Cohen R, Sironi F, Livesey M, Gillingwater T, Highley J, et al.
Acta Neuropathol
. 2022 Jul;
144(3):437-464.
PMID: 35876881
Dysfunction and degeneration of synapses is a common feature of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). A GGGGCC hexanucleotide repeat expansion in the C9ORF72 gene is the main genetic...
3.
Marchi P, Marrone L, Brasseur L, Coens A, Webster C, Bousset L, et al.
Life Sci Alliance
. 2022 May;
5(9).
PMID: 35568435
Dipeptide repeat (DPR) proteins are aggregation-prone polypeptides encoded by the pathogenic GGGGCC repeat expansion in the gene, the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. In...
4.
Fernandes J, Franco N, Grierson A, Hultgren J, Furley A, Olsson I
BMJ Open Sci
. 2022 Jan;
3(1):e000016.
PMID: 35047680
Objectives: The amyotrophic lateral sclerosis (ALS) research community was one of the first to adopt methodology guidelines to improve preclinical research reproducibility. We here present the results of a systematic...
5.
Derrick C, Pollitt E, Sevilla Uruchurtu A, Hussein F, Grierson A, Noel E
Development
. 2021 Sep;
148(20).
PMID: 34568948
During early vertebrate heart development, the heart transitions from a linear tube to a complex asymmetric structure, a morphogenetic process that occurs simultaneously with growth of the heart. Cardiac growth...
6.
K Lysyganicz P, Pooranachandran N, Liu X, Adamson K, Zielonka K, Elworthy S, et al.
Front Cell Dev Biol
. 2021 Jul;
9:676214.
PMID: 34268305
Cilia are evolutionarily highly conserved organelles with important functions in many organs. The extracellular component of the cilium protruding from the plasma membrane comprises an axoneme composed of microtubule doublets,...
7.
Sardina F, Pisciottani A, Ferrara M, Valente D, Casella M, Crescenzi M, et al.
Life Sci Alliance
. 2020 Oct;
3(12).
PMID: 33106322
Hereditary Spastic Paraplegia (HSP) is a neurodegenerative disease most commonly caused by autosomal dominant mutations in the gene encoding the microtubule-severing protein spastin. We hypothesise that -HSP is attributable to...
8.
Gibson J, Prajsnar T, Hill C, Tooke A, Serba J, Tonge R, et al.
Autophagy
. 2020 Jun;
17(6):1448-1457.
PMID: 32559122
Macroautophagy/autophagy functions to degrade cellular components and intracellular pathogens. Autophagy receptors, including SQSTM1/p62, target intracellular pathogens. is a significant pathogen of humans, especially in immunocompromise. may use neutrophils as a...
9.
Webster C, Smith E, Grierson A, De Vos K
Small GTPases
. 2016 Oct;
9(5):399-408.
PMID: 27768524
A GGGGCC hexanucleotide repeat expansion in the first intron of the C9orf72 gene is the most common genetic defect associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) (C9ALS/FTD)....
10.
Webster C, Smith E, Bauer C, Moller A, Hautbergue G, Ferraiuolo L, et al.
EMBO J
. 2016 Jun;
35(15):1656-76.
PMID: 27334615
A GGGGCC hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD). C9orf72 encodes two C9orf72 protein isoforms of...