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Andrew J Franjesevic

Explore the profile of Andrew J Franjesevic including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Franjesevic A, Sillart S, Beck J, Vyas S, Callam C, Hadad C
Chemistry . 2018 Nov; 25(21):5337-5371. PMID: 30444932
Organophosphorus (OP) nerve agents and pesticides present significant threats to civilian and military populations. OP compounds include the nefarious G and V chemical nerve agents, but more commonly, civilians are...
2.
Zhuang Q, Franjesevic A, Corrigan T, Coldren W, Dicken R, Sillart S, et al.
J Med Chem . 2018 Jun; 61(16):7034-7042. PMID: 29870665
After the inhibition of acetylcholinesterase (AChE) by organophosphorus (OP) nerve agents, a dealkylation reaction of the phosphylated serine, referred to as aging, can occur. When aged, known reactivators of OP-inhibited...