Andrew J Benie
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Explore the profile of Andrew J Benie including associated specialties, affiliations and a list of published articles.
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25
Citations
291
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Recent Articles
1.
Jensen V, Schefe L, Jacobsen H, Molck A, Almholt K, Sjogren I, et al.
Int J Toxicol
. 2022 Aug;
41(6):455-475.
PMID: 36036386
N9-GP/Rebinyn/Refixia is an approved PEGylated (polyethylene glycol-conjugated) recombinant human factor IX intended for prophylactic and/or on-demand treatment in adults and children with haemophilia B. A juvenile neurotoxicity study was conducted...
2.
Buckley S, Baekdal T, Vegge A, Maarbjerg S, Pyke C, Ahnfelt-Ronne J, et al.
Sci Transl Med
. 2018 Nov;
10(467).
PMID: 30429357
Oral administration of therapeutic peptides is hindered by poor absorption across the gastrointestinal barrier and extensive degradation by proteolytic enzymes. Here, we investigated the absorption of orally delivered semaglutide, a...
3.
Fogt Hjorth C, Norrman M, Wahlund P, Benie A, Petersen B, Jessen C, et al.
J Pharm Sci
. 2016 Feb;
105(4):1376-86.
PMID: 26921119
A specific covalently linked dimeric species of insulin high molecular weight products (HMWPs), formed during prolonged incubation of a neutral pharmaceutical formulation of human insulin, were characterized in terms of...
4.
Kjaerulff L, Benie A, Hoeck C, Gotfredsen C, Sorensen O
J Magn Reson
. 2016 Jan;
263:101-107.
PMID: 26774647
A novel method, Spin-State-Selective (S(3)) HMBC, for accurate measurement of homonuclear coupling constants is introduced. As characteristic for S(3) techniques, S(3) HMBC yields independent subspectra corresponding to particular passive spin...
5.
Blaum B, Wunsche W, Benie A, Kusov Y, Peters H, Gauss-Muller V, et al.
Nucleic Acids Res
. 2011 Dec;
40(7):3042-55.
PMID: 22156376
Oligonucleotides as short as 6 nt in length have been shown to bind specifically and tightly to proteins and affect their biological function. Yet, sparse structural data are available for...
6.
Sickmann H, Waagepetersen H, Schousboe A, Benie A, Bouman S
J Cereb Blood Flow Metab
. 2010 Apr;
30(8):1527-37.
PMID: 20424632
Obesity and type 2 diabetes have reached epidemic proportions; however, scarce information about how these metabolic syndromes influence brain energy and neurotransmitter homeostasis exist. The objective of this study was...
7.
Nielsen A, Jorgensen F, Olsen L, Christensen S, Benie A, Bjornholm T, et al.
Biopolymers
. 2010 Mar;
94(2):192-205.
PMID: 20225303
To generate a library covering a relatively wide area of the chemical space, molecular descriptors, and multivariate data analysis were combined to select the building blocks required for generating a...
8.
Meier S, Benie A, Duus J, Sorensen O
J Magn Reson
. 2009 Jul;
200(2):340-3.
PMID: 19604710
3D H2BC is introduced for heteronuclear assignment on natural abundance samples even for biomolecules up to at least 10 kDa in low millimolar concentrations as an overnight experiment using the...
9.
Blume A, Fitzen M, Benie A, Peters T
Carbohydr Res
. 2009 Apr;
344(12):1567-74.
PMID: 19362294
Hexokinase catalyzes the phosphorylation of glucose and is the first enzyme in glycolysis. To investigate enzyme-ligand interactions in yeast hexokinase isoform PII under physiological conditions, we utilized the technique of...
10.
Meier S, Benie A, Duus J, Sorensen O
Chemphyschem
. 2009 Mar;
10(6):893-5.
PMID: 19288490
NMR artifact purging: Modern NMR experiments depend on efficient coherence transfer pathways for their sensitivity and on suppression of undesired pathways leading to artifacts for their spectral clarity. A novel...