Andrew D Rouillard
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Explore the profile of Andrew D Rouillard including associated specialties, affiliations and a list of published articles.
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20
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6613
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Recent Articles
11.
Gundersen G, Jones M, Rouillard A, Kou Y, Monteiro C, Feldmann A, et al.
Bioinformatics
. 2015 May;
31(18):3060-2.
PMID: 25971742
Motivation: Identification of differentially expressed genes is an important step in extracting knowledge from gene expression profiling studies. The raw expression data from microarray and other high-throughput technologies is deposited...
12.
Maayan A, Rouillard A, Clark N, Wang Z, Duan Q, Kou Y
Trends Pharmacol Sci
. 2014 Aug;
35(9):450-60.
PMID: 25109570
Data sets from recent large-scale projects can be integrated into one unified puzzle that can provide new insights into how drugs and genetic perturbations applied to human cells are linked...
13.
Duan Q, Wang Z, Fernandez N, Rouillard A, Tan C, Benes C, et al.
Bioinformatics
. 2014 Aug;
30(22):3289-90.
PMID: 25100688
Summary: Recently, several high profile studies collected cell viability data from panels of cancer cell lines treated with many drugs applied at different concentrations. Such drug sensitivity data for cancer...
14.
Rouillard A, Holmes J
Prog Biophys Mol Biol
. 2014 Jul;
115(2-3):235-43.
PMID: 25009995
Following myocardial infarction, damaged muscle is gradually replaced by collagenous scar tissue. The structural and mechanical properties of the scar are critical determinants of heart function, as well as the...
15.
Duan Q, Flynn C, Niepel M, Hafner M, Muhlich J, Fernandez N, et al.
Nucleic Acids Res
. 2014 Jun;
42(Web Server issue):W449-60.
PMID: 24906883
For the Library of Integrated Network-based Cellular Signatures (LINCS) project many gene expression signatures using the L1000 technology have been produced. The L1000 technology is a cost-effective method to profile...
16.
Rouillard A, Holmes J
Biophys J
. 2014 Feb;
106(4):932-43.
PMID: 24559996
Because fibroblasts deposit the collagen matrix that determines the mechanical integrity of scar tissue, altering fibroblast invasion could alter wound healing outcomes. Anisotropic mechanical boundary conditions (restraint, stretch, or tension)...
17.
Rouillard A, Holmes J
J Physiol
. 2012 Apr;
590(18):4585-602.
PMID: 22495588
Effective management of healing and remodelling after myocardial infarction is an important problem in modern cardiology practice. We have recently shown that the level of infarct anisotropy is a critical...
18.
Fomovsky G, Rouillard A, Holmes J
J Mol Cell Cardiol
. 2012 Mar;
52(5):1083-90.
PMID: 22418281
Following myocardial infarction, the mechanical properties of the healing infarct are an important determinant of heart function and the risk of progression to heart failure. In particular, mechanical anisotropy (having...
19.
Rouillard A, Berglund C, Lee J, Polacheck W, Tsui Y, Bonassar L, et al.
Tissue Eng Part C Methods
. 2010 Aug;
17(2):173-9.
PMID: 20704471
Methods for seeding high-viability (>85%) three-dimensional (3D) alginate-chondrocyte hydrogel scaffolds are presented that employ photocrosslinking of methacrylate-modified alginate with the photoinitiator VA-086. Comparison with results from several other photoinitiators, including...
20.
Rouillard A, Tsui Y, Polacheck W, Lee J, Bonassar L, Kirby B
Biomacromolecules
. 2010 Aug;
11(8):2184-9.
PMID: 20690725
No abstract available.