Andrew C Adey
Overview
Explore the profile of Andrew C Adey including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
30
Citations
1364
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Ren T, Chen C, Danilov A, Liu S, Guan X, Du S, et al.
bioRxiv
. 2023 Mar;
PMID: 36993424
Accurately identifying phenotype-relevant cell subsets from heterogeneous cell populations is crucial for delineating the underlying mechanisms driving biological or clinical phenotypes. Here, by deploying a learning with rejection strategy, we...
12.
OConnell B, Nichols R, Pokholok D, Thomas J, Acharya S, Nishida A, et al.
Genome Res
. 2023 Feb;
33(2):208-217.
PMID: 36792372
Here we present advancements in single-cell combinatorial indexed Assay for Transposase Accessible Chromatin (sciATAC) to measure chromatin accessibility that leverage nanowell chips to achieve atlas-scale cell throughput (>10 cells) at...
13.
Romine K, MacPherson K, Cho H, Kosaka Y, Flynn P, Byrd K, et al.
Leukemia
. 2023 Jan;
37(3):580-592.
PMID: 36681742
Many acute myeloid leukemia (AML) patients exhibit hallmarks of immune exhaustion, such as increased myeloid-derived suppressor cells, suppressive regulatory T cells and dysfunctional T cells. Similarly, we have identified the...
14.
Nichols R, OConnell B, Mulqueen R, Thomas J, Woodfin A, Acharya S, et al.
Nat Commun
. 2022 Dec;
13(1):7627.
PMID: 36494343
DNA methylation is a key epigenetic property that drives gene regulatory programs in development and disease. Current single-cell methods that produce high quality methylomes are expensive and low throughput without...
15.
Co M, Barnard R, Jahncke J, Grindstaff S, Fedorov L, Adey A, et al.
J Neurosci
. 2022 Aug;
42(37):7166-7181.
PMID: 35944998
T-Box Brain Transcription Factor 1 (TBR1) plays essential roles in brain development, mediating neuronal migration, fate specification, and axon tract formation. While heterozygous loss-of-function and missense mutations are associated with...
16.
Mighell T, Nishida A, OConnell B, Miller C, Grindstaff S, Thornton C, et al.
CRISPR J
. 2022 Jul;
5(4):548-557.
PMID: 35833801
Targeted sequencing remains a valuable technique for clinical and research applications. However, many existing technologies suffer from pervasive guanine-cytosine (GC) sequence content bias, high input DNA requirements, and high cost...
17.
Eksi S, Chitsazan A, Sayar Z, Thomas G, Fields A, Kopp R, et al.
Nat Commun
. 2021 Dec;
12(1):7292.
PMID: 34911933
Identifying precise molecular subtypes attributable to specific stages of localized prostate cancer has proven difficult due to high levels of heterogeneity. Bulk assays represent a population-average, which mask the heterogeneity...
18.
Sun D, Guan X, Moran A, Wu L, Qian D, Schedin P, et al.
Nat Biotechnol
. 2021 Nov;
40(4):527-538.
PMID: 34764492
Single-cell RNA sequencing (scRNA-seq) distinguishes cell types, states and lineages within the context of heterogeneous tissues. However, current single-cell data cannot directly link cell clusters with specific phenotypes. Here we...
19.
Adey A
Genome Res
. 2021 Oct;
31(10):1693-1705.
PMID: 34599003
It has been just over 10 years since the initial description of transposase-based methods to prepare high-throughput sequencing libraries, or "tagmentation," in which a hyperactive transposase is used to simultaneously...
20.
Bates T, Leier H, Lyski Z, McBride S, Coulter F, Weinstein J, et al.
Nat Commun
. 2021 Aug;
12(1):5135.
PMID: 34446720
SARS-CoV-2 and its variants continue to infect hundreds of thousands every day despite the rollout of effective vaccines. Therefore, it is essential to understand the levels of protection that these...