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Andrew Barazia

Explore the profile of Andrew Barazia including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 118
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Recent Articles
1.
Barazia A, Monks C
Methods Mol Biol . 2022 Jan; 2415:245-252. PMID: 34972959
Mitosis is one of the most fundamental processes of life, allowing organisms to grow, develop, and evolve. Acquiring microscopic images and understanding the detailed mechanism of this process is critical...
2.
Li J, Kumari T, Barazia A, Jha V, Jeong S, Olson A, et al.
J Exp Med . 2021 Nov; 219(1). PMID: 34751735
The interaction between neutrophils and endothelial cells is critical for the pathogenesis of vascular inflammation. However, the regulation of neutrophil adhesive function remains not fully understood. Intravital microscopy demonstrates that...
3.
Kim K, Tseng A, Barazia A, Italiano J, Cho J
Blood . 2016 Dec; 129(2):209-225. PMID: 27903531
Downstream regulatory element antagonist modulator (DREAM), a transcriptional repressor, is known to modulate pain responses. However, it is unknown whether DREAM is expressed in anucleate platelets and plays a role...
4.
Kim K, Li J, Barazia A, Tseng A, Youn S, Abbadessa G, et al.
Haematologica . 2016 Oct; 102(2):246-259. PMID: 27758820
Previous studies identified the Ser/Thr protein kinase, AKT, as a therapeutic target in thrombo-inflammatory diseases. Here we report that specific inhibition of AKT with ARQ 092, an orally-available AKT inhibitor...
5.
Barazia A, Li J, Kim K, Shabrani N, Cho J
Blood . 2015 Aug; 126(22):2511-7. PMID: 26265698
Heterotypic cell-cell adhesion and aggregation mediate vaso-occlusive events in patients with sickle cell disease (SCD). Although hydroxyurea (HU), an inducer of fetal hemoglobin, is the main therapy for treatment of...
6.
Li J, Kim K, Barazia A, Tseng A, Cho J
Cell Mol Life Sci . 2015 Feb; 72(14):2627-43. PMID: 25650236
Platelets primarily mediate hemostasis and thrombosis, whereas leukocytes are responsible for immune responses. Since platelets interact with leukocytes at the site of vascular injury, thrombosis and vascular inflammation are closely...
7.
Kim K, Barazia A, Cho J
J Vis Exp . 2013 Apr; (74). PMID: 23609348
Interaction of activated platelets and leukocytes (mainly neutrophils) on the activated endothelium mediates thrombosis and vascular inflammation. During thrombus formation at the site of arteriolar injury, platelets adherent to the...