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Vijayprakash Manickam

Explore the profile of Vijayprakash Manickam including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 138
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Recent Articles
1.
Manickam V, Maity S, Murali S, Gawande D, Stothert A, Batalkina L, et al.
Front Cell Neurosci . 2024 Nov; 18:1486740. PMID: 39539341
Cochlear ribbon synapses between sensory inner hair cells (IHCs) and spiral ganglion neurons (SGNs) are vulnerable to rapid and primary damage and/or loss due to noise overexposure. Such damaged ribbon...
2.
Manickam V, Gawande D, Stothert A, Clayman A, Batalkina L, Warchol M, et al.
J Neurosci . 2023 Feb; 43(12):2075-2089. PMID: 36810227
Resident cochlear macrophages rapidly migrate into the inner hair cell synaptic region and directly contact the damaged synaptic connections after noise-induced synaptopathy. Eventually, such damaged synapses are spontaneously repaired, but...
3.
Manickam V, Dhawan U, Singh D, Gupta M, Subramanian M
Front Pharmacol . 2022 Jun; 13:888300. PMID: 35721222
Atherosclerosis is a chronic lipid-driven inflammatory condition of the arteries and is a leading cause of stroke, myocardial infarction, and other peripheral arterial diseases. Plant products rich in polyphenols such...
4.
Li J, Kumari T, Barazia A, Jha V, Jeong S, Olson A, et al.
J Exp Med . 2021 Nov; 219(1). PMID: 34751735
The interaction between neutrophils and endothelial cells is critical for the pathogenesis of vascular inflammation. However, the regulation of neutrophil adhesive function remains not fully understood. Intravital microscopy demonstrates that...
5.
Dhawan U, Bhattacharya P, Narayanan S, Manickam V, Aggarwal A, Subramanian M
Arterioscler Thromb Vasc Biol . 2021 Aug; 41(10):2598-2615. PMID: 34348488
Objective: Hypercholesterolemia-induced NETosis and accumulation of neutrophil extracellular traps (NETs) in the atherosclerotic lesion exacerbates inflammation and is causally implicated in plaque progression. We investigated whether hypercholesterolemia additionally impairs the...
6.
Jha V, Kumari T, Manickam V, Assar Z, Olson K, Min J, et al.
Antioxid Redox Signal . 2021 Jun; 35(13):1093-1115. PMID: 34074138
Protein disulfide isomerase (PDI) and endoplasmic reticulum oxidoreductase 1 (ERO1) are crucial for oxidative protein folding in the endoplasmic reticulum (ER). These enzymes are frequently overexpressed and secreted, and they...
7.
Manickam V, Dhakshinamoorthy V, Perumal E
Neurochem Res . 2019 Apr; 44(7):1533-1548. PMID: 30941547
Iron oxide (FeO) nanoparticles (NPs) attract the attention of clinicians for its unique magnetic and paramagnetic properties, which are exclusively used in neurodiagnostics and therapeutics among the other biomedical applications....
8.
Manickam V, Dhakshinamoorthy V, Perumal E
J Mol Neurosci . 2018 Jan; 64(3):352-362. PMID: 29368134
Iron oxide (FeO) nanoparticles (NPs) with its unique magnetic and paramagnetic properties are popular in biomedical applications. Some of their neurotoxic mechanisms due to repeated administration are proven. However, we...
9.
Manickam V, Periyasamy M, Dhakshinamoorthy V, Panneerselvam L, Perumal E
Chem Biol Interact . 2017 Oct; 278:54-64. PMID: 28993115
The cardiotoxicity of iron oxide nanoparticles (FeO-NPs) in mice was investigated. The mice were intraperitoneally administered with FeO-NPs at the dose of 25 and 50 mg/kg bw for 30 days...
10.
Dhakshinamoorthy V, Manickam V, Perumal E
Neurotox Res . 2017 Mar; 32(2):187-203. PMID: 28321581
Iron oxide nanoparticles (FeO-NPs) are widely used in various biomedical applications, extremely in neurotheranostics. Simultaneously, FeO-NP usage is of alarming concern, as its exposure to living systems causes deleterious effects...