Andres Mendez-Lucas
Overview
Explore the profile of Andres Mendez-Lucas including associated specialties, affiliations and a list of published articles.
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18
Citations
869
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Recent Articles
11.
Rodriguez-Carballo E, Gamez B, Mendez-Lucas A, Sanchez-Freutrie M, Zorzano A, Bartrons R, et al.
FASEB J
. 2015 Jan;
29(4):1414-25.
PMID: 25550462
The skeleton acts as an endocrine organ that regulates energy metabolism and calcium and phosphorous homeostasis through the secretion of osteocalcin (Oc) and fibroblast growth factor 23 (FGF23). However, evidence...
12.
Mendez-Lucas A, Hyrossova P, Novellasdemunt L, Vinals F, Perales J
J Biol Chem
. 2014 Jun;
289(32):22090-102.
PMID: 24973213
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), encoded by the nuclear PCK2 gene, links TCA cycle intermediates and glycolytic pools through the conversion of mitochondrial oxaloacetate into phosphoenolpyruvate. In the liver PEPCK-M adjoins...
13.
Santana-Codina N, Carretero R, Sanz-Pamplona R, Cabrera T, Guney E, Oliva B, et al.
Mol Cell Proteomics
. 2013 Apr;
12(8):2111-25.
PMID: 23625662
Bone metastasis is the most common distant relapse in breast cancer. The identification of key proteins involved in the osteotropic phenotype would represent a major step toward the development of...
14.
Mendez-Lucas A, Duarte J, Sunny N, Satapati S, He T, Fu X, et al.
J Hepatol
. 2013 Mar;
59(1):105-13.
PMID: 23466304
Background & Aims: Hepatic gluconeogenesis helps maintain systemic energy homeostasis by compensating for discontinuities in nutrient supply. Liver-specific deletion of cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) abolishes gluconeogenesis from mitochondrial substrates, deregulates...
15.
Novellasdemunt L, Tato I, Navarro-Sabate A, Ruiz-Meana M, Mendez-Lucas A, Perales J, et al.
J Biol Chem
. 2013 Mar;
288(15):10640-51.
PMID: 23457334
Reciprocal regulation of metabolism and signaling allows cells to modulate their activity in accordance with their metabolic resources. Thus, amino acids could activate signal transduction pathways that control cell metabolism....
16.
Satapati S, Sunny N, Kucejova B, Fu X, He T, Mendez-Lucas A, et al.
J Lipid Res
. 2012 Apr;
53(6):1080-92.
PMID: 22493093
The manner in which insulin resistance impinges on hepatic mitochondrial function is complex. Although liver insulin resistance is associated with respiratory dysfunction, the effect on fat oxidation remains controversial, and...
17.
Vidal-Alabro A, Gomez-Valades A, Mendez-Lucas A, Llorens J, Bartrons R, Bermudez J, et al.
Int J Endocrinol
. 2011 Dec;
2011:707928.
PMID: 22194744
Recent reports point out the importance of the complex GK-GKRP in controlling glucose and lipid homeostasis. Several GK mutations affect GKRP binding, resulting in permanent activation of the enzyme. We...
18.
Gomez-Valades A, Mendez-Lucas A, Vidal-Alabro A, Blasco F, Chillon M, Bartrons R, et al.
Diabetes
. 2008 Apr;
57(8):2199-210.
PMID: 18443203
Objective: Cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C; encoded by Pck1) catalyzes the first committed step in gluconeogenesis. Extensive evidence demonstrates a direct correlation between PEPCK-C activity and glycemia control. Therefore, we aimed...