Andrej Alendar
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Explore the profile of Andrej Alendar including associated specialties, affiliations and a list of published articles.
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8
Citations
542
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Recent Articles
1.
Pierattini B, DAgostino S, Bon C, Peruzzo O, Alendar A, Codino A, et al.
Mol Ther Nucleic Acids
. 2023 May;
32:402-414.
PMID: 37187707
SINEUPs are natural and synthetic antisense long non-coding RNAs (lncRNAs) selectively enhancing target mRNAs translation by increasing their association with polysomes. This activity requires two RNA domains: an embedded inverted...
2.
Tsagkogeorga G, Santos-Rosa H, Alendar A, Leggate D, Rausch O, Kouzarides T, et al.
Commun Biol
. 2022 Aug;
5(1):868.
PMID: 36008532
RNA methylation plays an important role in functional regulation of RNAs, and has thus attracted an increasing interest in biology and drug discovery. Here, we collected and collated transcriptomic, proteomic,...
3.
Alendar A, Berns A
Genes Dev
. 2021 Nov;
35(21-22):1403-1430.
PMID: 34725129
Chromatin is highly dynamic, undergoing continuous global changes in its structure and type of histone and DNA modifications governed by processes such as transcription, repair, replication, and recombination. Members of...
4.
Alendar A, Lambooij J, Bhaskaran R, Lancini C, Song J, van Vugt H, et al.
PLoS One
. 2020 May;
15(5):e0233394.
PMID: 32453735
Chromodomain helicase DNA-binding (CHD) chromatin remodelers regulate transcription and DNA repair. They govern cell-fate decisions during embryonic development and are often deregulated in human pathologies. Chd1-8 show upon germline disruption...
5.
Pandolfini L, Barbieri I, Bannister A, Hendrick A, Andrews B, Webster N, et al.
Mol Cell
. 2019 Apr;
74(6):1278-1290.e9.
PMID: 31031083
7-methylguanosine (m7G) is present at mRNA caps and at defined internal positions within tRNAs and rRNAs. However, its detection within low-abundance mRNAs and microRNAs (miRNAs) has been hampered by a...
6.
Cannizzaro E, Bannister A, Han N, Alendar A, Kouzarides T
FEBS Lett
. 2018 May;
592(13):2308-2322.
PMID: 29782654
DDX3X is a multifunctional RNA helicase with documented roles in different cancer types. Here, we demonstrate that DDX3X plays an oncogenic role in breast cancer cells by modulating the cell...
7.
Perera G, Ainali C, Semenova E, Hundhausen C, Barinaga G, Kassen D, et al.
Sci Transl Med
. 2014 Feb;
6(223):223ra22.
PMID: 24523322
Cytokines are critical checkpoints of inflammation. The treatment of human autoimmune disease has been revolutionized by targeting inflammatory cytokines as key drivers of disease pathogenesis. Despite this, there exist numerous...
8.
Nawijn M, Alendar A, Berns A
Nat Rev Cancer
. 2010 Dec;
11(1):23-34.
PMID: 21150935
Pim oncogenes are overexpressed in a wide range of tumours from a haematological and epithelial origin. Pim genes encode serine/threonine kinases that have been shown to counteract the increased sensitivity...