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Andreia Brandao

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Articles 19
Citations 397
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Recent Articles
1.
Peixoto A, Ferreira D, Miranda A, Relvas-Santos M, Freitas R, Veth T, et al.
iScience . 2025 Feb; 28(2):111758. PMID: 39906564
Bladder tumors with aggressive characteristics often present microenvironmental niches marked by low oxygen levels (hypoxia) and limited glucose supply due to inadequate vascularization. The molecular mechanisms facilitating cellular adaptation to...
2.
Cotton S, Ferreira D, Relvas-Santos M, Brandao A, Afonso L, Miranda A, et al.
Mol Oncol . 2024 Nov; 19(3):635-658. PMID: 39508360
Colorectal cancer (CRC) cells express sialylated Lewis antigens (sLe), crucial for metastasis via E-selectin binding. However, these glycoepitopes lack cancer specificity, and E-selectin-targeted glycoproteins remain largely unknown. Here, we established...
3.
Silva M, Ferreira L, Bras N, Torres L, Brandao A, Pinheiro M, et al.
J Biomed Sci . 2024 Jul; 31(1):74. PMID: 39014450
Background: Prostate cancer (PrCa) is the most frequently diagnosed cancer in men. Variants in known moderate- to high-penetrance genes explain less than 5% of the cases arising at early-onset (< ...
4.
Santos M, Lima L, Carvalho S, Brandao A, Barroso F, Cruz A, et al.
Int J Mol Sci . 2024 May; 25(10). PMID: 38791151
P-glycoprotein (P-GP) is a transporter molecule expressed on the apical surface of capillary endothelial cells of the Blood-Brain Barrier (BBB), whose activity heavily influences drug distribution, including antidepressants. This transporter...
5.
Wang A, Shen J, Rodriguez A, Saunders E, Chen F, Janivara R, et al.
Nat Genet . 2023 Nov; 55(12):2065-2074. PMID: 37945903
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry...
6.
Paulo P, Cardoso M, Brandao A, Pinto P, Falconi A, Pinheiro M, et al.
Genes Chromosomes Cancer . 2023 Jul; 62(12):710-720. PMID: 37436117
Prostate cancer (PrCa) is one of the three most frequent and deadliest cancers worldwide. The discovery of PARP inhibitors for the treatment of tumors with deleterious variants in homologous recombination...
7.
Pascoal S, Goncalves A, Brandao A, Rocha D, Oliveira S, Monteiro F, et al.
Int J Dent . 2023 Jun; 2022:8252696. PMID: 37361340
Introduction: There is a growing demand for more aesthetic, comfortable, and faster orthodontic treatments, and clear aligners emerged as a solution to fulfill this need. However, the effectiveness of clear...
8.
Cardoso M, Maia S, Brandao A, Sahasrabudhe R, Lott P, Belter N, et al.
Br J Cancer . 2022 Dec; 128(6):1077-1085. PMID: 36564567
Background: Prostate cancer (PrCa) is one of the most hereditable human cancers, however, only a small fraction of patients has been shown to carry deleterious variants in known cancer predisposition...
9.
Gaiteiro C, Soares J, Relvas-Santos M, Peixoto A, Ferreira D, Paulo P, et al.
Theranostics . 2022 May; 12(7):3150-3177. PMID: 35547758
Bladder cancer (BC) management demands the introduction of novel molecular targets for precision medicine. Cell surface glycoprotein CD44 has been widely studied as a potential biomarker of BC aggressiveness and...
10.
Barbosa A, Pinto P, Peixoto A, Guerra J, Pinheiro M, Santos C, et al.
Front Oncol . 2021 Oct; 11:754094. PMID: 34660321
Genetic testing to detect somatic alterations is usually performed on formalin-fixed paraffin-embedded tumor samples. However, tumor molecular profiling through ctDNA analysis may be particularly interesting with the emergence of targeted...