Anna H Bizard
Overview
Explore the profile of Anna H Bizard including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
613
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Recent Articles
1.
Martin C, Sarlos K, Logan C, Thakur R, Parry D, Bizard A, et al.
Am J Hum Genet
. 2024 May;
111(5):996.
PMID: 38701747
No abstract available.
2.
Hertz E, Vega I, Kruse T, Wang Y, Hendriks I, Bizard A, et al.
Nat Struct Mol Biol
. 2023 Jul;
30(9):1303-1313.
PMID: 37474739
SUMOylation regulates numerous cellular processes, but what represents the essential functions of this protein modification remains unclear. To address this, we performed genome-scale CRISPR-Cas9-based screens, revealing that the BLM-TOP3A-RMI1-RMI2 (BTRR)-PICH...
3.
Meijering A, Sarlos K, Nielsen C, Witt H, Harju J, Kerklingh E, et al.
Nature
. 2022 Jul;
607(7920):E23.
PMID: 35798956
No abstract available.
4.
Meijering A, Sarlos K, Nielsen C, Witt H, Harju J, Kerklingh E, et al.
Nature
. 2022 May;
605(7910):545-550.
PMID: 35508652
In preparation for mitotic cell division, the nuclear DNA of human cells is compacted into individualized, X-shaped chromosomes. This metamorphosis is driven mainly by the combined action of condensins and...
5.
Bakx J, Biebricher A, King G, Christodoulis P, Sarlos K, Bizard A, et al.
Nat Commun
. 2022 Feb;
13(1):584.
PMID: 35102151
Topoisomerase IIIα is a type 1A topoisomerase that forms a complex with RMI1 and RMI2 called TRR in human cells. TRR plays an essential role in resolving DNA replication and...
6.
Bizard A, Hickson I
J Biol Chem
. 2020 Apr;
295(20):7138-7153.
PMID: 32277049
The double-helical structure of genomic DNA is both elegant and functional in that it serves both to protect vulnerable DNA bases and to facilitate DNA replication and compaction. However, these...
7.
Achuthankutty D, Thakur R, Haahr P, Hoffmann S, Drainas A, Bizard A, et al.
J Cell Biol
. 2019 Oct;
218(12):3943-3953.
PMID: 31615875
The ATR kinase is a master regulator of the cellular response to DNA replication stress. Activation of ATR relies on dual pathways involving the TopBP1 and ETAA1 proteins, both of...
8.
Bizard A, Allemand J, Hassenkam T, Paramasivam M, Sarlos K, Singh M, et al.
Nat Struct Mol Biol
. 2019 Apr;
26(4):267-274.
PMID: 30936532
All known eukaryotic topoisomerases are only able to relieve torsional stress in DNA. Nevertheless, it has been proposed that the introduction of positive DNA supercoiling is required for efficient sister-chromatid...
9.
Albers E, Sbroggio M, Pladevall-Morera D, Bizard A, Avram A, Gonzalez P, et al.
Cell Rep
. 2018 Sep;
24(12):3274-3284.
PMID: 30232008
PICH is a DNA translocase necessary for the resolution of ultrafine anaphase DNA bridges and to ensure the fidelity of chromosomal segregation. Here, we report the generation of an animal...
10.
Martin C, Sarlos K, Logan C, Thakur R, Parry D, Bizard A, et al.
Am J Hum Genet
. 2018 Sep;
103(3):456.
PMID: 30193137
No abstract available.