Andreas Kloetgen
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Explore the profile of Andreas Kloetgen including associated specialties, affiliations and a list of published articles.
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44
Citations
1699
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Recent Articles
1.
Wiendl H, Barkhof F, Montalban X, Achiron A, Derfuss T, Chan A, et al.
Front Immunol
. 2025 Feb;
16:1512189.
PMID: 39963134
Background And Objectives: Cladribine tablets (CladT) represent an effective immune reconstitution therapy, administered in short treatment courses over two consecutive years. To better understand the amplitude of immune changes, we...
2.
St Paul M, Saibil S, Kates M, Han S, Lien S, Laister R, et al.
Cell Rep Med
. 2024 Mar;
5(3):101465.
PMID: 38460518
The manipulation of T cell metabolism to enhance anti-tumor activity is an area of active investigation. Here, we report that activating the amino acid starvation response in effector CD8 T ...
3.
Murphy D, Salataj E, Di Giammartino D, Rodriguez-Hernaez J, Kloetgen A, Garg V, et al.
Nat Struct Mol Biol
. 2023 Dec;
31(1):125-140.
PMID: 38053013
Mammalian embryogenesis commences with two pivotal and binary cell fate decisions that give rise to three essential lineages: the trophectoderm, the epiblast and the primitive endoderm. Although key signaling pathways...
4.
Murphy D, Salataj E, Di Giammartino D, Rodriguez-Hernaez J, Kloetgen A, Garg V, et al.
bioRxiv
. 2023 Aug;
PMID: 37577543
Mammalian embryogenesis commences with two pivotal and binary cell fate decisions that give rise to three essential lineages, the trophectoderm (TE), the epiblast (EPI) and the primitive endoderm (PrE). Although...
5.
Shamloo S, Kloetgen A, Petroulia S, Hockemeyer K, Sievers S, Tsirigos A, et al.
Biomedicines
. 2023 Jul;
11(7.
PMID: 37509693
The incidence of melanoma, being one of the most commonly occurring cancers, has been rising since the past decade. Patients at advanced stages of the disease have very poor prognoses,...
6.
Bamezai S, Pulikkottil A, Yadav T, Vegi N, Mueller J, Mark J, et al.
Blood
. 2023 May;
142(1):90-105.
PMID: 37146239
RNA-binding proteins (RBPs) form a large and diverse class of factors, many members of which are overexpressed in hematologic malignancies. RBPs participate in various processes of messenger RNA (mRNA) metabolism...
7.
Papafragkos I, Grigoriou M, Boon L, Kloetgen A, Hatzioannou A, Verginis P
Front Immunol
. 2022 Aug;
13:889075.
PMID: 36032139
Myeloid-derived suppressor cells (MDSCs) are myeloid precursors that exert potent immunosuppressive properties in cancer. Despite the extensive knowledge on mechanisms implicated in mobilization, recruitment, and function of MDSCs, their therapeutic...
8.
Thandapani P, Kloetgen A, Witkowski M, Glytsou C, Lee A, Wang E, et al.
Nature
. 2021 Dec;
601(7893):428-433.
PMID: 34937946
Although deregulation of transfer RNA (tRNA) biogenesis promotes the translation of pro-tumorigenic mRNAs in cancers, the mechanisms and consequences of tRNA deregulation in tumorigenesis are poorly understood. Here we use...
9.
Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, et al.
Cell Metab
. 2021 Dec;
34(1):1-2.
PMID: 34895500
Zickler et al. describe SARS-CoV-2 RNA in post-mortem samples of human adipose tissue. In the hamster model, SARS-CoV-2 propagation in adipose tissue leads to specific changes in lipid metabolism, which...
10.
Aronson B, Scourzic L, Shah V, Swanzey E, Kloetgen A, Polyzos A, et al.
Dev Cell
. 2021 Oct;
56(22):3052-3065.e5.
PMID: 34710357
Loss of imprinting (LOI) results in severe developmental defects, but the mechanisms preventing LOI remain incompletely understood. Here, we dissect the functional components of the imprinting control region of the...