Andreas B den Hartigh
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Explore the profile of Andreas B den Hartigh including associated specialties, affiliations and a list of published articles.
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26
Citations
805
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Recent Articles
1.
Anderson M, den Hartigh A, Loomis W, Fink S
Cell Death Discov
. 2024 Nov;
10(1):470.
PMID: 39550359
Inflammasome formation, arising from pathogen or internal activating signals, is a key step in canonical pyroptosis, a gasdermin-mediated inflammatory cell death. Inhibition of pyroptosis has great clinical relevance due to...
2.
den Hartigh A, Loomis W, Anderson M, Frolund B, Fink S
Commun Biol
. 2024 Mar;
7(1):310.
PMID: 38467884
No abstract available.
3.
den Hartigh A, Loomis W, Anderson M, Frolund B, Fink S
Commun Biol
. 2023 Oct;
6(1):1010.
PMID: 37798443
Pyroptosis is a cell death process that causes inflammation and contributes to numerous diseases. Pyroptosis is mediated by caspase-1 family proteases that cleave the pore-forming protein gasdermin D, causing plasma...
4.
Oda J, den Hartigh A, Jackson S, Tronco A, Fink S
mBio
. 2023 Jun;
14(4):e0054023.
PMID: 37306512
The cellular processes that support human coronavirus replication and contribute to the pathogenesis of severe disease remain incompletely understood. Many viruses, including coronaviruses, cause endoplasmic reticulum (ER) stress during infection....
5.
Anderson M, den Hartigh A, Fink S
Methods Mol Biol
. 2023 Apr;
2641:1-16.
PMID: 37074637
Pyroptosis is a regulated form of cell death that leads to inflammation and plays a role in many different diseases. Pyroptosis was initially defined by the dependence on caspase-1, a...
6.
Ravindran V, Wagoner J, Athanasiadis P, den Hartigh A, Sidorova J, Ianevski A, et al.
Brief Bioinform
. 2022 Oct;
23(6).
PMID: 36305426
The ongoing coronavirus disease 2019 (COVID-19) pandemic has highlighted the need to better understand virus-host interactions. We developed a network-based method that expands the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-host...
7.
den Hartigh A, Fink S
Methods Mol Biol
. 2022 Sep;
2543:179-189.
PMID: 36087268
Pyroptosis is a highly regulated inflammatory form of cell death that plays a role in many different diseases, including cancer. Pyroptosis was initially described to be mediated by caspase-1, which...
8.
Kolpikova E, Tronco A, den Hartigh A, Jackson K, Iwawaki T, Fink S
Viruses
. 2020 Mar;
12(3).
PMID: 32138181
Zika virus (ZIKV) is an emergent member of the family which causes severe congenital defects and other major sequelae, but the cellular processes that support ZIKV replication are incompletely understood....
9.
Loomis W, den Hartigh A, Cookson B, Fink S
Cell Death Dis
. 2019 Apr;
10(4):326.
PMID: 30975978
Pyroptosis is a programmed process of proinflammatory cell death mediated by caspase-1-related proteases that cleave the pore-forming protein, gasdermin D, causing cell lysis and release of inflammatory intracellular contents. The...
10.
den Hartigh A, Fink S
Curr Protoc Immunol
. 2018 Jul;
122(1):e52.
PMID: 30028908
Pyroptosis is a form of programmed pro-inflammatory cell death that plays a protective role in the host response to infection, but can also promote pathogenic inflammation. Pyroptosis is mediated by...