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Renee M Tsolis

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Articles 135
Citations 8371
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Recent Articles
1.
Lazaro-Anton L, Carvalho T, Pirillo E, Byndloss M, Diaz-Ochoa V, Young B, et al.
Infect Immun . 2025 Mar; :e0006025. PMID: 40071915
infects the placenta of its natural bovine host, which results in abortion and transmission of infection to other cattle and to humans. While the metabolism of during chronic infection of...
2.
Cespedes N, Tsolis R, Piliponsky A, Luckhart S
Trends Parasitol . 2024 Dec; 41(1):38-51. PMID: 39658487
Malaria predisposes to concomitant bacteremia, resulting in increased mortality risk. Previous studies indicated that malaria causes structural changes in the intestine, induces tolerogenic immune responses, inhibits neutrophil recruitment, suppresses innate...
3.
Radlinski L, Rogers A, Bechtold L, Masson H, Nguyen H, Larabi A, et al.
Proc Natl Acad Sci U S A . 2024 Nov; 121(47):e2417232121. PMID: 39546570
The gut microbiota produces high concentrations of antimicrobial short-chain fatty acids (SCFAs) that restrict the growth of invading microorganisms. The enteric pathogen serovar () Typhimurium triggers inflammation in the large...
4.
Rogers A, Radlinski L, Nguyen H, Tiffany C, Carvalho T, Masson H, et al.
Cell Host Microbe . 2024 Aug; 32(10):1774-1786.e9. PMID: 39181125
The gut microbiota prevents harmful microbes from entering the body, a function known as colonization resistance. The enteric pathogen Salmonella enterica serovar (S.) Typhimurium uses its virulence factors to break...
5.
Sun Y, Ferreira F, Reid B, Zhu K, Ma L, Young B, et al.
Nat Microbiol . 2024 Aug; 9(10):2653-2665. PMID: 39164392
Salmonella translocate to the gut epithelium via microfold cells lining the follicle-associated epithelium (FAE). How Salmonella localize to the FAE is not well characterized. Here we use live imaging and...
6.
Poveda-Urkixo I, Mena-Bueno S, Ramirez G, Zabalza-Barangua A, Tsolis R, Grillo M
Vaccine . 2024 May; 42(17):3710-3720. PMID: 38755066
One of the main causes of human brucellosis is Brucella melitensis infecting small ruminants. To date, Rev1 is the only vaccine successfully used to control ovine and caprine brucellosis. However,...
7.
Lokken-Toyli K, Diaz-Ochoa V, Camacho L, Stull-Lane A, Van Hecke A, Mooney J, et al.
Nat Microbiol . 2024 Feb; 9(3):727-736. PMID: 38374245
In sub-Saharan Africa, multidrug-resistant non-typhoidal Salmonella serovars are a common cause of fatal bloodstream infection. Malnutrition is a predisposing factor, but the underlying mechanisms are unknown. Here we show that...
8.
Carvalho T, Toledo F, Bautista D, Silva M, Oliveira J, Lima P, et al.
mBio . 2024 Jan; 15(3):e0325223. PMID: 38289074
Importance: A previously unknown mechanism by which pericytes modulate inflammation was discovered. The absence of pericytes or blocking interaction between pericytes and endothelium through connexin 43 results in stronger inflammation,...
9.
Eng S, Nonnecke E, de Lorimier A, Ali M, Tsolis R, Bevins C, et al.
Proc Natl Acad Sci U S A . 2023 Nov; 120(47):e2312453120. PMID: 37956278
To mediate critical host-microbe interactions in the human small intestine, Paneth cells constitutively produce abundant levels of α-defensins and other antimicrobials. We report that the expression profile of these antimicrobials...
10.
Moreno E, Middlebrook E, Altamirano-Silva P, Al Dahouk S, Araj G, Arce-Gorvel V, et al.
J Clin Microbiol . 2023 Jul; 61(8):e0043823. PMID: 37395662
Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living,...