Andrea Zanetti
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Explore the profile of Andrea Zanetti including associated specialties, affiliations and a list of published articles.
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10
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62
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Recent Articles
1.
Zanetti A, Dujardin G, Fares-Taie L, Amiel J, Roger J, Audo I, et al.
Nat Commun
. 2024 Nov;
15(1):10096.
PMID: 39572588
Here we conduct a study involving 12 individuals with retinal dystrophy, neurological impairment, and skeletal abnormalities, with special focus on GPATCH11, a lesser-known G-patch domain-containing protein, regulator of RNA metabolism....
2.
de Gaetano M, Tighe C, Gahan K, Zanetti A, Chen J, Newson J, et al.
J Med Chem
. 2021 Jun;
64(13):9193-9216.
PMID: 34138563
Failure to resolve inflammation underlies many prevalent pathologies. Recent insights have identified lipid mediators, typified by lipoxins (LXs), as drivers of inflammation resolution, suggesting potential therapeutic benefit. We report the...
3.
Zanetti A, Schwertz G, de Oliveira M, Gomez Fernandez M, Amara Z, Cossy J
J Org Chem
. 2021 May;
86(11):7603-7608.
PMID: 33983733
A regioselective Pd-catalyzed allylic oxidation of amorphadiene, a key precursor to the antimalarial drug artemisinin, is described. Amorphadiene can be obtained in high yields by fermentation, but it is currently...
4.
Gomez Fernandez M, de Oliveira M, Zanetti A, Schwertz G, Cossy J, Amara Z
Org Lett
. 2021 Apr;
23(15):5593-5598.
PMID: 33900782
A new access to artemisinin is reported based on a selective photochemical hydrothiolation of amorphadiene, a waste product of the industrial semisynthetic route. This study highlights the discovery of two...
5.
Schwertz G, Zanetti A, de Oliveira M, Gomez Fernandez M, Amara Z, Cossy J
J Org Chem
. 2020 Jul;
85(15):9607-9613.
PMID: 32643937
A formal synthesis of artemisinin starting from amorphadiene is described. This new route relies on the development of a catalytic chemo- and diastereoselective hydrosilylation. The practicability of this method is...
6.
Zanetti A, Chaumont-Olive P, Schwertz G, de Oliveira M, Gomez Fernandez M, Amara Z, et al.
Org Process Res Dev
. 2020 May;
24(5):850-855.
PMID: 32454580
Artemisinin is an important drug to fight malaria. It is produced either by extraction or via a semisynthetic route involving enzyme engineering. A key intermediate to produce artemisinin by the...
7.
Schwertz G, Zanetti A, de Oliveira M, Gomez Fernandez M, Dioury F, Cossy J, et al.
Tetrahedron
. 2019 Feb;
75(6):743-748.
PMID: 30739959
Amorphadiene is a natural product involved in the biosynthesis of the antimalarial drug artemisinin. A convenient four-step synthesis of amorphadiene, starting from commercially available dihydroartemisinic acid, is reported. The targeted...
8.
de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, et al.
Eur J Med Chem
. 2018 Nov;
162:80-108.
PMID: 30419493
Lipoxins (LXs) are endogenously generated eicosanoids with potent bio-actions consistent with attenuation of inflammation. The costly synthesis and metabolic instability of LXs may limit their therapeutic potential. Here we report...
9.
Palmerini L, Bagala F, Zanetti A, Klenk J, Becker C, Cappello A
Sensors (Basel)
. 2015 May;
15(5):11575-86.
PMID: 26007719
Falls among older people are a widely documented public health problem. Automatic fall detection has recently gained huge importance because it could allow for the immediate communication of falls to...
10.
Zanetti A, Grata M, Etling E, Panday R, Villanueva F, Toma C
Tissue Eng Part C Methods
. 2015 Jan;
21(7):683-92.
PMID: 25567723
Mesenchymal stem cells (MSCs) have been extensively explored in a variety of regenerative medicine applications. The relatively large size of MSCs expanded in tissue culture flasks leads to retention in...