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Andrea Welling

Explore the profile of Andrea Welling including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1419
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Recent Articles
1.
Seemann N, Welling A, Rustenbeck I
Mol Cell Endocrinol . 2017 Dec; 472:97-106. PMID: 29208420
The antimalarial agent, mefloquine, inhibits the function of connexin Cx36 gap junctions and hemichannels and has thus become a tool to investigate their physiological relevance in pancreatic islets. In view...
2.
Szabat M, Modi H, Ramracheya R, Girbinger V, Chan F, Lee J, et al.
R Soc Open Sci . 2016 Mar; 2(12):150306. PMID: 27019722
Insulin production is the central feature of functionally mature and differentiated pancreatic β-cells. Reduced insulin transcription and dedifferentiation have been implicated in type 2 diabetes, making drugs that could reverse...
3.
Yang G, Shi Y, Yu J, Li Y, Yu L, Welling A, et al.
Cell Mol Life Sci . 2014 Oct; 72(6):1197-207. PMID: 25292336
The voltage-gated Ca(2+) (CaV) channel acts as a key player in β cell physiology and pathophysiology. β cell CaV channels undergo hyperactivation subsequent to exposure to type 1 diabetic (T1D)...
4.
Zhang Q, Chibalina M, Bengtsson M, Groschner L, Ramracheya R, Rorsman N, et al.
J Physiol . 2014 Aug; 592(21):4677-96. PMID: 25172946
Mouse pancreatic β- and α-cells are equipped with voltage-gated Na(+) currents that inactivate over widely different membrane potentials (half-maximal inactivation (V0.5) at -100 mV and -50 mV in β- and...
5.
Langeslag M, Malsch P, Welling A, Kress M
Pflugers Arch . 2014 Jan; 466(11):2153-65. PMID: 24463703
Neuropathic pain and pain arising from local inflammation are characterized by increased release of inflammatory mediators like interleukin-6 (IL-6) by immune cells. The levels of IL-6 is increased in various...
6.
Bellin M, Casini S, Davis R, DAniello C, Haas J, Ward-van Oostwaard D, et al.
EMBO J . 2013 Nov; 32(24):3161-75. PMID: 24213244
Patient-specific induced pluripotent stem cells (iPSCs) will assist research on genetic cardiac maladies if the disease phenotype is recapitulated in vitro. However, genetic background variations may confound disease traits, especially...
7.
Leiss V, Friebe A, Welling A, Hofmann F, Lukowski R
Diabetes . 2010 Oct; 60(1):148-56. PMID: 20978093
Objective: The physiologic significance of the nitric oxide (NO)/cGMP signaling pathway in islets is unclear. We hypothesized that cGMP-dependent protein kinase type I (cGKI) is directly involved in the secretion...
8.
Moretti A, Bellin M, Welling A, Jung C, Lam J, Bott-Flugel L, et al.
N Engl J Med . 2010 Jul; 363(15):1397-409. PMID: 20660394
Background: Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. In long-QT...
9.
Blaich A, Welling A, Fischer S, Wegener J, Kostner K, Hofmann F, et al.
Proc Natl Acad Sci U S A . 2010 May; 107(22):10285-9. PMID: 20479240
Activity-dependent means of altering calcium (Ca(2)(+)) influx are assumed to be of great physiological consequence, although definitive tests of this assumption have only begun to emerge. Facilitation and inactivation offer...
10.
Higuchi T, Anton M, Dumler K, Seidl S, Pelisek J, Saraste A, et al.
J Nucl Med . 2009 Jun; 50(7):1088-94. PMID: 19525455
Unlabelled: There is a need for in vivo monitoring of cell engraftment and survival after cardiac cell transplantation therapy. This study assessed the feasibility and usefulness of combined PET and...