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Tae-Seong Lee

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Articles 6
Citations 147
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Recent Articles
1.
Lee T, Ono K, Miyamoto S, Hadama T, Arita M
J UOEH . 2006 Sep; 28(3):277-86. PMID: 16981404
The L-type Ca2+ channel has a unique kinetic property known as voltage-dependent facilitation. Many researchers have repeatedly investigated the mechanism in response to the voltage-dependent facilitation since the first observation...
2.
Lee T, Kaku T, Takebayashi S, Uchino T, Miyamoto S, Hadama T, et al.
Pharmacology . 2006 Aug; 78(1):11-20. PMID: 16899990
We compared detailed efficacy of efonidipine and nifedipine, dihydropyridine analogues, and mibefradil using recombinant T- and L-type Ca2+ channels expressed separately in mammalian cells. All these Ca2+ channel antagonists blocked...
3.
Lee T, Karl R, Moosmang S, Lenhardt P, Klugbauer N, Hofmann F, et al.
J Biol Chem . 2006 Jul; 281(35):25560-7. PMID: 16820363
Calcium-dependent facilitation of L-type calcium channels has been reported to depend on the function of calmodulin kinase II. In contrast, the mechanism for voltage-dependent facilitation is not clear. In HEK...
4.
Uchino T, Lee T, Kaku T, Yamashita N, Noguchi T, Ono K
Pharmacology . 2005 Apr; 74(4):174-81. PMID: 15855830
Effects of bepridil on the low voltage-activated T-type Ca2+ channel (CaV3.2) current stably expressed in human embryonic kidney (HEK)-293 cells were examined using patch-clamp techniques. Bepridil potently inhibited ICa,T with...
5.
Wegener J, Schulla V, Lee T, Koller A, Feil S, Feil R, et al.
FASEB J . 2004 May; 18(10):1159-61. PMID: 15132976
Mice deficient in the smooth muscle Cav1.2 calcium channel (SMACKO, smooth muscle alpha1c-subunit calcium channel knockout) have a severely reduced micturition and an increased bladder mass. L-type calcium current, protein,...
6.
Kaku T, Lee T, Arita M, Hadama T, Ono K
Jpn J Physiol . 2003 Oct; 53(3):165-72. PMID: 14529577
Calcium channels are essential for excitation-contraction coupling and pacemaker potentials in cardiac muscle cells. Whereas L-type Ca(2+) channels have been extensively studied, T-type channels have been poorly characterized in cardiac...