Andrea Martella
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Explore the profile of Andrea Martella including associated specialties, affiliations and a list of published articles.
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30
Citations
560
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Recent Articles
1.
Lodde L, Zandara C, Martella A, Manchia M, Paribello P, Mascia I, et al.
Front Psychiatry
. 2025 Feb;
15:1395899.
PMID: 39911553
Objectives: Crimes committed on the Internet and social networks are rising, and the phenomenon is complex. Knowledge of context would be useful for professionals in cases that need psychiatric assessment....
2.
Kuhn B, Ritter M, Hornsperger B, Bell C, Kocer B, Rombach D, et al.
J Med Chem
. 2024 Oct;
67(20):18448-18464.
PMID: 39360636
Monoacylglycerol lipase (MAGL) is a key enzyme involved in the metabolism of the endogenous signaling ligand 2-arachidonoylglycerol, a neuroprotective endocannabinoid intimately linked to central nervous system (CNS) disorders associated with...
3.
Oling D, Lan-Chow-Wing O, Martella A, Gilberto S, Chi J, Cooper E, et al.
ACS Synth Biol
. 2022 Jul;
11(7):2229-2237.
PMID: 35797032
Rapid and flexible plasmid construct generation at scale is one of the most limiting first steps in drug discovery projects. These hurdles can partly be overcome by adopting modular DNA...
4.
James J, Jones S, Martella A, Luo Y, Fisher D, Cai Y
ACS Synth Biol
. 2022 Jan;
11(2):587-595.
PMID: 35061373
With applications from functional genomics to the production of therapeutic biologics, libraries of mammalian expression vectors have become a cornerstone of modern biological investigation and engineering. Multiple modular vector platforms...
5.
Luo Y, James J, Jones S, Martella A, Cai Y
ACS Synth Biol
. 2022 Jan;
11(2):579-586.
PMID: 35050610
Computational design tools are the cornerstone of synthetic biology and have underpinned its rapid development over the past two decades. As the field has matured, the scale of biological investigation...
6.
Martella A, Fisher D
CRISPR J
. 2021 Feb;
4(1):43-57.
PMID: 33616442
In complex multicellular systems, gene expression is regulated at multiple stages through interconnected complex molecular pathways and regulatory networks. Transcription is the first step in gene expression and is subject...
7.
Zhou J, Mock E, Al Ayed K, Di X, Kantae V, Burggraaff L, et al.
J Med Chem
. 2020 Aug;
63(17):9340-9359.
PMID: 32787138
The phospholipase A and acyltransferase (PLAAT) family of cysteine hydrolases consists of five members, which are involved in the Ca-independent production of -acylphosphatidylethanolamines (NAPEs). NAPEs are lipid precursors for bioactive...
8.
Mock E, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie G, Kantae V, et al.
Nat Chem Biol
. 2020 May;
16(6):667-675.
PMID: 32393901
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper...
9.
Matjusaitis M, Wagstaff L, Martella A, Baranowski B, Blin C, Gogolok S, et al.
Stem Cell Reports
. 2019 Nov;
13(6):1053-1067.
PMID: 31708478
Cell lineage reprogramming via transgene overexpression of key master regulatory transcription factors has been well documented. However, the poor efficiency and lack of fidelity of this approach is problematic. Synthetic...
10.
Yu X, Martella A, Kolovos P, Stevens M, Stadhouders R, Grosveld F, et al.
Haematologica
. 2019 Oct;
105(7):1802-1812.
PMID: 31582556
GATA1 is an essential transcriptional regulator of myeloid hematopoietic differentiation towards red blood cells. During erythroid differentiation, GATA1 forms different complexes with other transcription factors such as LDB1, TAL1, E2A...