Andrea L Matthis
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Explore the profile of Andrea L Matthis including associated specialties, affiliations and a list of published articles.
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10
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205
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Recent Articles
1.
McCauley H, Matthis A, Enriquez J, Nichol J, Sanchez J, Stone W, et al.
Nat Commun
. 2020 Sep;
11(1):4791.
PMID: 32963229
The ability to absorb ingested nutrients is an essential function of all metazoans and utilizes a wide array of nutrient transporters found on the absorptive enterocytes of the small intestine....
2.
Matthis A, Kaji I, Engevik K, Akiba Y, Kaunitz J, Montrose M, et al.
Dig Dis Sci
. 2019 Sep;
65(1):119-131.
PMID: 31515722
Background: Peptic ulcers recur, suggesting that ulcer healing may leave tissue predisposed to subsequent damage. In mice, we have identified that the regenerated epithelium found after ulcer healing will remain...
3.
Hanyu H, Engevik K, Matthis A, Ottemann K, Montrose M, Aihara E
Infect Immun
. 2019 Jul;
87(9).
PMID: 31262979
is a pathogen that chronically colonizes the stomachs of approximately half of the world's population and contributes to the development of gastric inflammation. We demonstrated previously that uses motility to...
4.
Engevik K, Hanyu H, Matthis A, Zhang T, Frey M, Oshima Y, et al.
J Physiol
. 2019 Mar;
597(10):2673-2690.
PMID: 30912855
Key Points: Determining the signalling cascade of epithelial repair, using murine gastric organoids, allows definition of regulatory processes intrinsic to epithelial cells, at the same time as validating and dissecting...
5.
Aihara E, Medina-Candelaria N, Hanyu H, Matthis A, Engevik K, Gurniak C, et al.
J Cell Sci
. 2018 Aug;
131(16).
PMID: 30072444
The role of the actin cytoskeleton in the sequence of physiological epithelial repair in the intact epithelium has yet to be elucidated. Here, we explore the role of actin in...
6.
Engevik K, Matthis A, Montrose M, Aihara E
Methods Mol Biol
. 2017 Dec;
1734:71-81.
PMID: 29288448
The advent of the gastric organoid culture system has provided a new model to emulate native epithelial tissue in vitro. Gastric organoids grow from isolated epithelial stem cells and develop...
7.
Aihara E, Matthis A, Karns R, Engevik K, Jiang P, Wang J, et al.
Cell Mol Gastroenterol Hepatol
. 2016 Oct;
2(5):625-647.
PMID: 27766298
Background & Aims: The peptic ulcer heals through a complex process, although the ulcer relapse often occurs several years later after healing. Our hypothesis is that even after visual evidence...
8.
Matthis A, Zhang B, Denson L, Yacyshyn B, Aihara E, Montrose M
Inflamm Bowel Dis
. 2016 Jul;
22(8):1793-802.
PMID: 27416043
Background: 5-aminosalicylic acid (5-ASA) is a classic anti-inflammatory drug for the treatment of ulcerative colitis. N-acetyltransferase (NAT) enzymes convert 5-ASA to its metabolite N-acetyl-5-ASA, and it is unresolved whether 5-ASA...
9.
Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid
Aihara E, Mahe M, Schumacher M, Matthis A, Feng R, Ren W, et al.
Sci Rep
. 2015 Nov;
5:17185.
PMID: 26597788
Leucine-rich repeat-containing G-protein coupled receptor 5-expressing (Lgr5(+)) cells have been identified as stem/progenitor cells in the circumvallate papillae, and single cultured Lgr5(+) cells give rise to taste cells. Here we...
10.
Aihara E, Closson C, Matthis A, Schumacher M, Engevik A, Zavros Y, et al.
PLoS Pathog
. 2014 Jul;
10(7):e1004275.
PMID: 25033386
Helicobacter pylori (H. pylori) is a pathogen contributing to peptic inflammation, ulceration, and cancer. A crucial step in the pathogenic sequence is when the bacterium first interacts with gastric tissue,...