Karen M Ottemann
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Explore the profile of Karen M Ottemann including associated specialties, affiliations and a list of published articles.
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69
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2061
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Recent Articles
1.
Yang C, Rodriguez Y Baena A, Manso B, Hu S, Lopez-Magana R, Ohanyan M, et al.
Microbiol Spectr
. 2024 Dec;
13(1):e0107324.
PMID: 39641542
Importance: Many bacteria signal to each other using quorum sensing signals. One type of signal is called autoinducer 2 (AI-2), which is produced and sensed by the LuxS enzyme found...
2.
Khan M, Rahman M, Xin Y, Mustafa A, Smith B, Ottemann K, et al.
ACS Pharmacol Transl Sci
. 2024 Oct;
7(10):3096-3107.
PMID: 39430314
Quantification of protein-ligand interactions is crucial for understanding the protein's biological function and for drug discovery. In this study, we employed three distinct approaches for determination of protein-ligand binding affinities...
3.
Liu X, Lertsethtakarn P, Mariscal V, Yildiz F, Ottemann K
mBio
. 2024 May;
15(6):e0044024.
PMID: 38700325
Importance: Chemotaxis signaling systems have been reported to contribute to biofilm formation in many bacteria; however, how they regulate biofilm formation remains largely unknown. Chemotaxis systems are composed of many...
4.
Sagoo J, Abedrabbo S, Liu X, Ottemann K
J Bacteriol
. 2024 Mar;
206(4):e0040623.
PMID: 38446058
Importance: Chemotactic motility, present in over half of bacteria, depends on chemotaxis signaling systems comprising receptors, kinases, and scaffold proteins. In , a stomach pathogen, chemotaxis is crucial for colonization,...
5.
Liu X, Tachiyama S, Zhou X, Mathias R, Bonny S, Khan M, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(4):e2317452121.
PMID: 38236729
Bacterial flagella and type IV pili (TFP) are surface appendages that enable motility and mechanosensing through distinct mechanisms. These structures were previously thought to have no components in common. Here,...
6.
Hu S, Giacopazzi S, Modlin R, Karplus K, Bernick D, Ottemann K
mBio
. 2023 Oct;
14(6):e0210523.
PMID: 37905805
Manipulating the genomes of bacteria is critical to many fields. Such manipulations are made by genetic engineering, which often requires new pieces of DNA to be added to the genome....
7.
Liu X, Roujeinikova A, Ottemann K
mBio
. 2023 Oct;
14(6):e0239623.
PMID: 37874157
No abstract available.
8.
Sagoo J, Abedrabbo S, Liu X, Ottemann K
bioRxiv
. 2023 May;
PMID: 37163056
The stomach pathogen utilizes two scaffold proteins, CheW and CheV1, to build critical chemotaxis arrays. Chemotaxis helps bacteria establish and maintain infection. Mutants lacking either of these chemotaxis proteins have...
9.
Hadjifrangiskou M, Liu J, Ottemann K, Roujeinikova A
Trends Microbiol
. 2023 May;
31(6):539-543.
PMID: 37127442
No abstract available.
10.
Hu S, Ottemann K
Nat Commun
. 2023 Mar;
14(1):1695.
PMID: 36973281
The complement system has long been appreciated for its role in bloodborne infections, but its activities in other places, including the gastrointestinal tract, remain elusive. Here, we report that complement...