Andrea J Schorn
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Explore the profile of Andrea J Schorn including associated specialties, affiliations and a list of published articles.
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8
Citations
341
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Recent Articles
1.
Herridge R, Dolata J, Migliori V, de Santis Alves C, Borges F, Schorn A, et al.
Nat Struct Mol Biol
. 2024 Sep;
32(2):277-286.
PMID: 39242979
Developmental epigenetic modifications in plants and animals are mostly reset during gamete formation but some are inherited from the germline. Small RNAs guide these epigenetic modifications but how inherited small...
2.
Herridge R, Dolata J, Migliori V, de Santis Alves C, Borges F, Schorn A, et al.
bioRxiv
. 2023 Jul;
PMID: 37398006
Epigenetic modifications that arise during plant and animal development, such as DNA and histone modification, are mostly reset during gamete formation, but some are inherited from the germline including those...
3.
He C, Bozler J, Janssen K, Wilusz J, Garcia B, Schorn A, et al.
Nat Struct Mol Biol
. 2020 Nov;
28(1):62-70.
PMID: 33230319
The ten-eleven translocation 2 (TET2) protein, which oxidizes 5-methylcytosine in DNA, can also bind RNA; however, the targets and function of TET2-RNA interactions in vivo are not fully understood. Using...
4.
Cullen H, Schorn A
Viruses
. 2020 Jul;
12(8).
PMID: 32718022
Endogenous retroviruses (ERVs) in mammals are closely related to infectious retroviruses and utilize host tRNAs as a primer for reverse transcription and replication, a hallmark of long terminal repeat (LTR)...
5.
Schorn A, Martienssen R
Mol Cell
. 2019 May;
74(3):415-417.
PMID: 31051138
Sultana et al. (2019) and Flasch et al. (2019) determined integration patterns of human LINE-1 (long interspersed element-1) retrotransposons highlighting their interaction with DNA replication guided by their 5'-TTTT/AA-3' integration...
6.
Schorn A, Martienssen R
Trends Cell Biol
. 2018 Jun;
28(10):793-806.
PMID: 29934075
tRNA fragments (tRFs) are a class of small, regulatory RNAs with diverse functions. 3'-Derived tRFs perfectly match long terminal repeat (LTR)-retroelements which use the 3'-end of tRNAs to prime reverse...
7.
Schorn A, Gutbrod M, LeBlanc C, Martienssen R
Cell
. 2017 Jul;
170(1):61-71.e11.
PMID: 28666125
Transposon reactivation is an inherent danger in cells that lose epigenetic silencing during developmental reprogramming. In the mouse, long terminal repeat (LTR)-retrotransposons, or endogenous retroviruses (ERV), account for most novel...
8.
Ingouff M, Selles B, Michaud C, Vu T, Berger F, Schorn A, et al.
Genes Dev
. 2017 Jan;
31(1):72-83.
PMID: 28115468
Cytosine methylation is a key epigenetic mark in many organisms, important for both transcriptional control and genome integrity. While relatively stable during somatic growth, DNA methylation is reprogrammed genome-wide during...