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Andrea I Doseff

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Articles 53
Citations 1641
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Recent Articles
1.
Chu Y, Lee Y, Gomez-Cano F, Gomez-Cano L, Zhou P, Doseff A, et al.
Plant Cell . 2024 Jun; 36(9):3709-3728. PMID: 38922302
Variation in gene expression levels is pervasive among individuals and races or varieties, and has substantial agronomic consequences, for example, by contributing to hybrid vigor. Gene expression level variation results...
2.
Sudhakaran M, Navarrete T, Mejia-Guerra K, Mukundi E, Eubank T, Grotewold E, et al.
Cell Death Dis . 2023 Dec; 14(12):824. PMID: 38092740
Triple-negative breast cancer (TNBC) is characterized by its aggressiveness and resistance to cancer-specific transcriptome alterations. Alternative splicing (AS) is a major contributor to the diversification of cancer-specific transcriptomes. The TNBC...
3.
Decot H, Sudhakaran M, Boismier E, Schilmiller A, Claucherty E, Doseff A, et al.
Foods . 2023 Oct; 12(20). PMID: 37893640
Industrial processing of tart cherries ( L.) produces bioproducts like cherry pits (CP), which contribute to adverse environmental effects. To identify sustainable strategies to minimize the environmental impact of cherry...
4.
Sudhakaran M, Doseff A
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982162
Cancer remains the second leading cause of death, accounting for approximately 20% of all fatalities. Evolving cancer cells and a dysregulated immune system create complex tumor environments that fuel tumor...
5.
Mohammadhosseinpour S, Weaver A, Sudhakaran M, Ho L, Le T, Doseff A, et al.
Cancers (Basel) . 2023 Jan; 15(2). PMID: 36672351
Triple-negative breast cancer (TNBC) is one of the deadliest forms of breast cancer. Investigating alternative therapies to increase survival rates for this disease is essential. To this end, the cytotoxic...
6.
Kariagina A, Doseff A
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555392
Flavones are natural phytochemicals broadly distributed in our diet. Their anti-inflammatory properties provide unique opportunities to control the innate immune system and inflammation. Here, we review the role of flavones...
7.
Misek S, Newbury P, Chekalin E, Paithankar S, Doseff A, Chen B, et al.
Mol Pharmacol . 2021 Nov; 101(1):1-12. PMID: 34732527
Most B-Raf proto-oncogene (BRAF)-mutant melanoma tumors respond initially to BRAF inhibitor (BRAFi)/mitogen-activated protein kinase kinase 1 inhibitor (MEKi) therapy, although few patients have durable long-term responses to these agents. The...
8.
Desmet N, Dhusia K, Qi W, Doseff A, Bhattacharya S, Gilad A
Biosensors (Basel) . 2021 Apr; 11(5). PMID: 33924783
In recent years, Synthetic Biology has emerged as a new discipline where functions that were traditionally performed by electronic devices are replaced by "cellular devices"; genetically encoded circuits constructed of...
9.
Voss O, Arango D, Tossey J, Villalona Calero M, Doseff A
Cell Death Dis . 2021 Mar; 12(4):287. PMID: 33731677
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selective killing of cancer cells underlines its anticancer potential. However, poor tolerability and resistance underscores the need to identify cancer-selective TRAIL-sensitizing agents. Apigenin, a...
10.
Sudhakaran M, Parra M, Stoub H, Gallo K, Doseff A
Biochem Pharmacol . 2020 Oct; 182:114259. PMID: 33011162
Acquired resistance to doxorubicin is a major hurdle in triple-negative breast cancer (TNBC) therapy, emphasizing the need to identify improved strategies. Apigenin and other structurally related dietary flavones are emerging...