Andrea Gorzanelli
Overview
Explore the profile of Andrea Gorzanelli including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
401
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0
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Recent Articles
1.
Careccia G, Saclier M, Tirone M, Ruggieri E, Principi E, Raffaghello L, et al.
Sci Transl Med
. 2021 Jun;
13(596).
PMID: 34078746
Muscular dystrophies (MDs) are a group of genetic diseases characterized by progressive muscle wasting associated to oxidative stress and persistent inflammation. It is essential to deepen our knowledge on the...
2.
Nair R, Mazza D, Brambilla F, Gorzanelli A, Agresti A, Bianchi M
Front Immunol
. 2018 Jul;
9:1463.
PMID: 29997623
Histones are the protein component of nucleosomes, which are the basic packing unit of chromatin. However, histones are also found in the blood, both as components of nucleosomes leaked out...
3.
Tirone M, Tran N, Ceriotti C, Gorzanelli A, Canepari M, Bottinelli R, et al.
J Exp Med
. 2017 Dec;
215(1):303-318.
PMID: 29203538
Inflammation and tissue regeneration follow tissue damage, but little is known about how these processes are coordinated. High Mobility Group Box 1 (HMGB1) is a nuclear protein that, when released...
4.
Antonelli A, Di Maggio S, Rejman J, Sanvito F, Rossi A, Catucci A, et al.
Biochim Biophys Acta Gen Subj
. 2016 Dec;
1861(2):354-364.
PMID: 27913191
Background: The membrane-bound isoform of the receptor for advanced glycation end products (FL-RAGE) is primarily expressed by alveolar epithelial cells and undergoes shedding by the protease ADAM10, giving rise to...
5.
Choi H, Tian M, Song F, Venereau E, Preti A, Park S, et al.
Mol Med
. 2015 Jun;
21:526-35.
PMID: 26101955
Salicylic acid (SA) and its derivatives have been used for millennia to reduce pain, fever and inflammation. In addition, prophylactic use of acetylsalicylic acid, commonly known as aspirin, reduces the...
6.
Burocchi A, Pittoni P, Gorzanelli A, Colombo M, Piconese S
Eur J Immunol
. 2012 Jan;
41(12):3615-26.
PMID: 22229156
Treg cells maintain the tumor microenvironment in an immunosuppressive state preventing an effective anti-tumor immune response. A possible strategy to overcome Treg-cell suppression focuses on OX40, a costimulatory molecule expressed...
7.
Piconese S, Costanza M, Tripodo C, Sangaletti S, Musio S, Pittoni P, et al.
J Autoimmun
. 2011 Oct;
37(4):300-10.
PMID: 21962567
Lymphnode swelling during immune responses is a transient, finely regulated tissue rearrangement, accomplished with the participation of the extracellular matrix. Here we show that murine and human reactive lymph nodes...
8.
Piconese S, Costanza M, Musio S, Tripodo C, Poliani P, Gri G, et al.
Lab Invest
. 2011 Feb;
91(4):627-41.
PMID: 21321538
Mast cell (MC)-deficient c-Kit mutant Kit(W/W-v) mice are protected against experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, suggesting a detrimental role for MCs in this disease. To...
9.
Piconese S, Pittoni P, Burocchi A, Gorzanelli A, Care A, Tripodo C, et al.
Eur J Immunol
. 2010 Sep;
40(10):2902-13.
PMID: 20806292
OX40 stimulation is known to enhance activation of effector T cells and to inhibit induction and suppressive function of Treg. Here we uncovered a novel role of OX40 in sustaining...
10.
Piconese S, Gri G, Tripodo C, Musio S, Gorzanelli A, Frossi B, et al.
Blood
. 2009 Aug;
114(13):2639-48.
PMID: 19643985
The development of inflammatory diseases implies inactivation of regulatory T (Treg) cells through mechanisms that still are largely unknown. Here we showed that mast cells (MCs), an early source of...