Andrea Conidi
Overview
Explore the profile of Andrea Conidi including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
572
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0
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Recent Articles
1.
Verploegh I, Conidi A, El Hassnaoui H, Verhoeven F, Korporaal A, Ntafoulis I, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337661
One of the main causes of poor prognoses in patient with glioblastoma (GBM) is drug resistance to current standard treatment, which includes chemoradiation and adjuvant temozolomide (TMZ). In addition, the...
2.
Bos E, Binda E, Verploegh I, Wembacher E, Hoefnagel D, Balvers R, et al.
Mol Cancer
. 2023 Aug;
22(1):129.
PMID: 37563568
Background: This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone Morphogenetic Protein 4 (hrBMP4) - an inhibitory regulator of cancer...
3.
Birkhoff J, Korporaal A, Brouwer R, Nowosad K, Milazzo C, Mouratidou L, et al.
Genes (Basel)
. 2023 Mar;
14(3).
PMID: 36980900
Functional perturbation and action mechanism studies have shown that the transcription factor Zeb2 controls cell fate decisions, differentiation, and/or maturation in multiple cell lineages in embryos and after birth. In...
4.
Verploegh I, Conidi A, Brouwer R, Balcioglu H, Karras P, Makhzami S, et al.
Neuro Oncol
. 2022 May;
24(12):2133-2145.
PMID: 35639831
Background: Glioblastoma (GBM) is the most aggressive primary brain tumor. Its cellular composition is very heterogeneous, with cells exhibiting stem-cell characteristics (GSCs) that co-determine therapy resistance and tumor recurrence. Bone...
5.
Birkhoff J, Huylebroeck D, Conidi A
Genes (Basel)
. 2021 Aug;
12(7).
PMID: 34356053
After its publication in 1999 as a DNA-binding and SMAD-binding transcription factor (TF) that co-determines cell fate in amphibian embryos, ZEB2 was from 2003 studied by embryologists mainly by documenting...
6.
de Haan W, Dheedene W, Apelt K, Decombas-Deschamps S, Vinckier S, Verhulst S, et al.
Cardiovasc Res
. 2021 Apr;
118(5):1262-1275.
PMID: 33909875
Aims: Hepatic capillaries are lined with specialized liver sinusoidal endothelial cells (LSECs) which support macromolecule passage to hepatocytes and prevent fibrosis by keeping hepatic stellate cells (HSCs) quiescent. LSEC specialization...
7.
Menuchin-Lasowski Y, Dagan B, Conidi A, Cohen-Gulkar M, David A, Ehrlich M, et al.
Dev Biol
. 2020 Sep;
468(1-2):80-92.
PMID: 32950463
The interplay between signaling molecules and transcription factors during retinal development is key to controlling the correct number of retinal cell types. Zeb2 (Sip1) is a zinc-finger multidomain transcription factor...
8.
Birkhoff J, Brouwer R, Kolovos P, Korporaal A, Bermejo-Santos A, Boltsis I, et al.
Hum Mol Genet
. 2020 Jul;
29(15):2535-2550.
PMID: 32628253
The transcription factor zinc finger E-box binding protein 2 (ZEB2) controls embryonic and adult cell fate decisions and cellular maturation in many stem/progenitor cell types. Defects in these processes in...
9.
Deryckere A, Stappers E, Dries R, Peyre E, van den Berghe V, Conidi A, et al.
Development
. 2020 Apr;
147(10).
PMID: 32253238
The transcription factor Zeb2 controls fate specification and subsequent differentiation and maturation of multiple cell types in various embryonic tissues. It binds many protein partners, including activated Smad proteins and...
10.
Dries R, Stryjewska A, Coddens K, Okawa S, Notelaers T, Birkhoff J, et al.
Stem Cells
. 2019 Nov;
38(2):202-217.
PMID: 31675135
Cooperative actions of extrinsic signals and cell-intrinsic transcription factors alter gene regulatory networks enabling cells to respond appropriately to environmental cues. Signaling by transforming growth factor type β (TGFβ) family...